ArticleAnnual review of public health2010
Genome-wide association studies and beyond.
Article in Annual review of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- How are social determinants of health integrated into epigenetic research? A systematic review.Social science & medicine (1982) · 2021Pooled it
- Pooled it
- A systematic review of cancer GWAS and candidate gene meta-analyses reveals limited overlap but similar effect sizes.European journal of human genetics : EJHG · 2014Pooled it
- Is Virulence GeneInfectious disease reports · 2026Article
- The development of type 2 diabetes amongst sibling pairs in the South-South region of Nigeria: The effect of genetics, environment and lifestyle.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Review
- NitroGene: privacy-preserving collaborative genomic analysis using AWS nitro enclaves.Bioinformatics advances · 2026Article
- Seeing the Small to Prevent the Big: The Role of Cerebral Microvessels in Ischemic Stroke Etiology and Prevention.Stroke research and treatment · 2026Review
- Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease.American journal of human genetics · 2025Article
- Unraveling the Complex Genomic Interplay of Sickle Cell Disease Among the Saudi Population: A Case-Control GWAS Analysis.International journal of molecular sciences · 2025Article
- Applying traditional and machine learning-based GWAS approaches for marker-trait identification in wheat.Frontiers in plant science · 2025Article
- Hereditary Patterns and Genetic Associations in Obsessive-Compulsive Disorder (OCD): Neuropsychiatric Insights, Genetic Influences, and Treatment Perspectives.Current gene therapy · 2025Review
- From Genomics to Metabolomics: Molecular Insights into Osteoporosis for Enhanced Diagnostic and Therapeutic Approaches.Biomedicines · 2024Review
- Impact of Epigenetics, Diet, and Nutrition-Related Pathologies on Wound Healing.International journal of molecular sciences · 2024Review
- Genome-Wide Association Study for Milk Somatic Cell Score in Holstein Friesian Cows in Slovenia.Animals : an open access journal from MDPI · 2024Article
- Review
- Review
- Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes.Metabolic brain disease · 2024Review
- Gene-Level Analysis of Anthracycline-Induced Cardiomyopathy in Cancer Survivors: A Report From COG-ALTE03N1, BMTSS, and CCSS.JACC. CardioOncology · 2023Article
- New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats.Scientific reports · 2023Article
21 more citing papers are in PubMed but not listed here.
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Authors and funding
1 author.
Funding
Abstract
Genome-wide association studies (GWAS) provide an important avenue for undertaking an agnostic evaluation of the association between common genetic variants and risk of disease. Recent advances in our understanding of human genetic variation and the technology to measure such variation have made GWAS feasible. Over the past few years a multitude of GWAS have identified and replicated many associated variants. These findings are enriching our knowledge about the genetic basis of disease and leading some to advocate using GWA study results for genetic testing. For many of the GWA study results, however, the underlying mechanisms remain unclear and the findings explain only a limited amount of heritability. These issues may be clarified by more detailed investigations, including analyses of less common variants, sequence-level data, and environmental exposures. Such studies should help clarify the potential value of genetic testing to the public's health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.