Evidence map›Paper›PMID 20234854›Full record

ArticleArchives of osteoporosis2009

Undertreatment of osteoporosis in the oldest old? A nationwide study of over 700,000 older people.

Kristina Johnell, Johan Fastbom

Open access · hybridAbstract read
In one paragraph

Article in Archives of osteoporosis, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. [Geriatric traumatology-Principles of orthogeriatrics].Chirurgie (Heidelberg, Germany) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Extensive undertreatment of osteoporosis in older Swedish women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
  8. [Management of osteoporosis after fragility fractures].Zeitschrift fur Gerontologie und Geriatrie · 2018
    Review
  9. Review
  10. Value of a coordinated management of osteoporosis via Fracture Liaison Service for the treatment of orthogeriatric patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2016
    Article
  11. Article
  12. Article
  13. [Proximal femoral fractures in the elderly].Zeitschrift fur Gerontologie und Geriatrie · 2015
    Review
  14. Review
  15. Article
  16. Magnitude of fragility fracture risk in the very old--are we meeting their needs? The Newcastle 85+ Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Observational
  17. Article
  18. Challenges in implementing and maintaining osteoporosis therapy.International journal of women's health · 2014
    Review
  19. Educational level and use of osteoporosis drugs in elderly men and women: a Swedish nationwide register-based study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kristina JohnellAging Research Center, Karolinska Institutet, Gävlegatan 16, 113 30 Stockholm, Sweden.
Johan Fastbom
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryWe analysed data from elderly people registered in the Swedish Prescribed Drug Register to investigate whether age is associated with use of osteoporosis drugs in a nationwide population. Our results indicate an undertreatment of osteoporosis, particularly with bisphosphonates, in the oldest old in Sweden.

introductionThe aim of this study was to investigate whether age is associated with use of osteoporosis drugs in a large population of older people.

methodsWe analysed data on age, sex, type of residential area (urban/rural) and dispensed drugs for people aged >/=75 years registered in the Swedish Prescribed Drug Register from October to December 2005 (n = 731,105). Multivariate logistic regression was used to analyse whether age was associated with use of osteoporosis drugs, after adjustment for type of residential area and number of other drugs (a proxy for comorbidity).

resultsOsteoporosis drugs were used by 16.1% of the women and 3.4% of the men. The probability of use of bisphosphonates declined with increasing age [ORwomen = 0.36 (95% CI 0.34-0.38) and ORmen = 0.46 (95% CI 0.37-0.56) for age >/=90 years vs. 75-79 years]. Raloxifene was also negatively associated with age. Calcium + vitamin D supplements, however, showed a divergent pattern regarding age. In women, the lowest likelihood of use of calcium + vitamin D supplements occurred in the oldest old (>/=90 years).

conclusionsOur results indicate an undertreatment of osteoporosis, particularly with bisphosphonates, in the oldest old in Sweden. Future research is needed for understanding the mechanisms behind this age effect.

Identifiers

PMID20234854
PMCPMC2836742
OpenAlexW2065661123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.