ReviewVascular health and risk management2010
Inhaled insulin: overview of a novel route of insulin administration.
Review in Vascular health and risk management, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Article
- Pulmonary route of administration is instrumental in developing therapeutic interventions against respiratory diseases.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Review
- A Review: The Prospect of Inhaled Insulin Therapy via Vibrating Mesh Technology to Treat Diabetes.International journal of environmental research and public health · 2020Review
- Capturing the Onset of Bacterial Pulmonary Infection in Acini-On-Chips.Advanced biosystems · 2019Article
- Assessing patients' acceptance of their medication to reveal unmet needs: results from a large multi-diseases study using a patient online community.Health and quality of life outcomes · 2018Observational
- Intravenous and Intratracheal Thyrotropin Releasing Hormone and Its Analog Taltirelin Reverse Opioid-Induced Respiratory Depression in Isoflurane Anesthetized Rats.The Journal of pharmacology and experimental therapeutics · 2018Article
- Exogenous insulin antibody syndrome (EIAS): a clinical syndrome associated with insulin antibodies induced by exogenous insulin in diabetic patients.Endocrine connections · 2018Review
- Pharmacokinetic and Pharmacodynamic Properties of a Novel Inhaled Insulin.Journal of diabetes science and technology · 2017Review
- Insulin administration: present strategies and future directions for a noninvasive (possibly more physiological) delivery.Drug design, development and therapy · 2015Review
- Advances in device and formulation technologies for pulmonary drug delivery.AAPS PharmSciTech · 2014Review
- Targeting inhaled therapy beyond the lungs.Respiration; international review of thoracic diseases · 2014Review
- Effect of cigarette smoke extract on insulin transport in alveolar epithelial cell line A549.Lung · 2012Article
- New technologies for diabetes: a review of the present and the future.International journal of pediatric endocrinology · 2012Article
- Chitosan-sodium lauryl sulfate nanoparticles as a carrier system for the in vivo delivery of oral insulin.AAPS PharmSciTech · 2011Article
- Inhaled insulin: A "puff" than a "shot" before meals.Journal of pharmacology & pharmacotherapeuticsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes is a chronic disease characterized by inadequate insulin secretion with resulting hyperglycemia. Diabetes complications include both microvascular and macrovascular disease, both of which are affected by optimal diabetes control. Many individuals with diabetes rely on subcutaneous insulin administration by injection or continuous infusion to control glucose levels. Novel routes of insulin administration are an area of interest in the diabetes field, given that insulin injection therapy is burdensome for many patients. This review will discuss pulmonary delivery of insulin via inhalation. The safety of inhaled insulin as well as the efficacy in comparison to subcutaneous insulin in the various populations with diabetes are covered. In addition, the experience and pitfalls that face the development and marketing of inhaled insulin are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.