Evidence map›Paper›PMID 20234195›Full record

ArticleAIDS (London, England)2010

Prolonged viral suppression without therapy in an HIV-1 seroconverter following early antiretroviral therapy and daily interleukin-2.

Joseph B Margolick, Hejab Imteyaz, Joel E Gallant, Susan J Langan, Jason B Dinoso, Janet Siliciano, Joel Blankson, Tricia L Nilles, Kendall A Smith, Linda G Apuzzo

Abstract readCase ReportsLetter
In one paragraph

Article in AIDS (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joseph B Margolick
Hejab Imteyaz
Joel E Gallant
Susan J Langan
Jason B Dinoso
Janet Siliciano
Joel Blankson
Tricia L Nilles
Kendall A Smith
Linda G Apuzzo

Funding

Multicenter Aids Cohort Study- Part B (Baltimore Site)U01AI035042 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T, MARGOLICK, JOSEPH B. · 1993 to 2018
$61.5M
Interleukin 2 as Immune Therapy in Early HIV InfectionR01AI054199 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MARGOLICK, JOSEPH B. · 2003 to 2005
$1.7M
HPK1 MEDIATED T CELL SIGNAL TRANSDUCTION MECHANISMSR01AI042532 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI TAN, TSE-HUA · 1998 to 2002
$1.0M
HPK1-Mediated Lymphocyte Signal Transduction MechanismsR56AI042532 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI TAN, TSE-HUA · 2005 to 2005
$300k
NIAID NIH HHS AI 042532NIAID NIH HHS AI 054199NIAID NIH HHS R01 AI042532NIAID NIH HHS R01 AI054199NIAID NIH HHS R56 AI042532NIAID NIH HHS U01 AI035042
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAntiretroviral Therapy, Highly ActiveBlotting, WesternHIV-1HIV SeropositivityHumansInterleukin-2MaleTreatment OutcomeInterleukin-2

Identifiers

PMID20234195
PMCPMC4565498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.