Evidence map›Paper›PMID 20234040›Full record

Trial reportBMJ (Clinical research ed.)2010

Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life.

Ludeke C Lambeek, Willem van Mechelen, Dirk L Knol, Patrick Loisel, Johannes R Anema

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02034864 (Comparison of the Effectiveness of 2 Manual Therapies on Functional Outcome in Sub-acute and Chronic Non-specific Low Back Pain at 3 Months), which is not on this map. Cited by 134 papers, 26 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 26 pooled it
24.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02034864 nacompletednot on this mapstarted 2014, after this paper: background citation

Comparison of the Effectiveness of 2 Manual Therapies on Functional Outcome in Sub-acute and Chronic Non-specific Low Back Pain at 3 Months : a Randomised Controlled Trial

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2014 to 2017Enrolled400ConditionsSubacute and Chronic Non-specific Low Back PainArmsOsteopathic manipulative treatment, Placebo of osteopathic manipulative treatment
3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 26 syntheses or guidelines pooled it, 292 citations in OpenAlex.

  1. Pooled it
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  4. Models of care for managing non-specific low back pain.The Cochrane database of systematic reviews · 2025
    Pooled it
  5. Rehabilitation of sick-listed LBP patients in occupational health with collaboration of the workplace.International journal of occupational medicine and environmental health · 2024
    Pooled it
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  7. Guideline
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  19. Radiofrequency denervation for chronic low back pain.The Cochrane database of systematic reviews · 2015
    Pooled it
  20. Workplace interventions to prevent work disability in workers on sick leave.The Cochrane database of systematic reviews · 2015
    Pooled it

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ludeke C LambeekDepartment of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands.
Willem van Mechelen
Dirk L Knol
Patrick Loisel
Johannes R Anema
EMGO Institute for Health and Care Research · NLPublic Health Ontario · CA

Funding

Canadian Institutes of Health Research FRN: 53909
6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of an integrated care programme, combining a patient directed and a workplace directed intervention, for patients with chronic low back pain.

designPopulation based randomised controlled trial.

settingPrimary care (10 physiotherapy practices, one occupational health service, one occupational therapy practice) and secondary care (five hospitals).

participants134 adults aged 18-65 sick listed for at least 12 weeks owing to low back pain.

interventionPatients were randomly assigned to usual care (n=68) or integrated care (n=66). Integrated care consisted of a workplace intervention based on participatory ergonomics, involving a supervisor, and a graded activity programme based on cognitive behavioural principles.

main outcome measuresThe primary outcome was the duration of time off work (work disability) due to low back pain until full sustainable return to work. Secondary outcome measures were intensity of pain and functional status.

resultsThe median duration until sustainable return to work was 88 days in the integrated care group compared with 208 days in the usual care group (P=0.003). Integrated care was effective on return to work (hazard ratio 1.9, 95% confidence interval 1.2 to 2.8, P=0.004). After 12 months, patients in the integrated care group improved significantly more on functional status compared with patients in the usual care group (P=0.01). Improvement of pain between the groups did not differ significantly.

conclusionThe integrated care programme substantially reduced disability due to chronic low back pain in private and working life. Trial registration Current Controlled Trials ISRCTN28478651.

Indexed as

AdolescentAdultAgedChronic DiseaseDelivery of Health Care, IntegratedFemaleHospitalizationHumansLow Back PainMaleMiddle AgedOccupational Health ServicesOccupational TherapyPatient CompliancePersons with DisabilitiesPhysical Therapy Modalities

Identifiers

PMID20234040
PMCPMC2840223
OpenAlexW2028702370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.