Evidence map›Paper›PMID 20232242›Full record

ReviewAIDS and behavior2010

Neurocognitive impairment and HIV risk factors: a reciprocal relationship.

Pria Anand, Sandra A Springer, Michael M Copenhaver, Frederick L Altice

Abstract readReview
In one paragraph

Review in AIDS and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 8 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 8 syntheses or guidelines pooled it, 151 citations in OpenAlex.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pria AnandDepartment of Medicine, Yale University School of Medicine, New Haven, CT 06510-2283, USA.
Sandra A Springer
Michael M Copenhaver
Frederick L Altice
Yale University · USUniversity of Connecticut · US

Funding

Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
Opiate Dependence, HIV and Adherence InterventionsK23DA019381 · NIDA · YALE UNIVERSITY · PI SPRINGER, SANDRA ANN · 2005 to 2009
$874k
Optimizing HIV Risk Reduction for HIV Positive IDUsK23DA017015 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI COPENHAVER, MICHAEL · 2003 to 2006
$619k
NIDA NIH HHS K23 DA017015NIDA NIH HHS K23 DA019381NIDA NIH HHS K23 DA17015NIDA NIH HHS K24 DA017072
6 · The paper itself

Abstract

Cognitive impairment among populations at risk for HIV poses a significant barrier to managing risk behaviors. The impact of HIV and several cofactors, including substance abuse and mental illness, on cognitive function is discussed in the context of HIV risk behaviors, medication adherence, and risk-reduction interventions. Literature suggests that cognitive impairment is intertwined in a close, reciprocal relationship with both risk behaviors and medication adherence. Not only do increased risk behaviors and suboptimal adherence exacerbate cognitive impairment, but cognitive impairment also reduces the effectiveness of interventions aimed at optimizing medication adherence and reducing risk. In order to be effective, risk-reduction interventions must therefore take into account the impact of cognitive impairment on learning and behavior.

Indexed as

Antiretroviral Therapy, Highly ActiveCognition DisordersHIV InfectionsHumansMedication AdherenceRisk FactorsRisk-TakingSubstance-Related Disorders

Identifiers

PMID20232242
PMCPMC2906682
OpenAlexW1970325459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.