ArticleJournal of biomolecular NMR2010
SAGA: rapid automatic mainchain NMR assignment for large proteins.
Article in Journal of biomolecular NMR, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Detecting and accounting for multiple sources of positional variance in peak list registration analysis and spin system grouping.Journal of biomolecular NMR · 2017Article
- Enhanced biosynthetically directed fractional carbon-13 enrichment of proteins for backbone NMR assignments.Protein expression and purification · 2015Article
- Non-Uniform Sampling and J-UNIO Automation for Efficient Protein NMR Structure Determination.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015Article
- Article
- Apoprotein Structure and Metal Binding Characterization of a de Novo Designed Peptide, α3DIV, that Sequesters Toxic Heavy Metals.Biochemistry · 2015Article
- Spectroscopic studies reveal that the heme regulatory motifs of heme oxygenase-2 are dynamically disordered and exhibit redox-dependent interaction with heme.Biochemistry · 2015Article
- APSY-NMR for protein backbone assignment in high-throughput structural biology.Journal of biomolecular NMR · 2015Article
- Fast and accurate resonance assignment of small-to-large proteins by combining automated and manual approaches.PLoS computational biology · 2015Article
- Chemical shift assignments of domain 4 from the phosphohexomutase from Pseudomonas aeruginosa suggest that freeing perturbs its coevolved domain interface.Biomolecular NMR assignments · 2014Article
- Automated robust and accurate assignment of protein resonances for solid state NMR.Journal of biomolecular NMR · 2014Article
- RASP: rapid and robust backbone chemical shift assignments from protein structure.Journal of biomolecular NMR · 2014Article
- EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data.Journal of biomolecular NMR · 2013Article
- The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.Biochemistry · 2013Article
- A unified NMR strategy for high-throughput determination of backbone fold of small proteins.Journal of structural and functional genomics · 2012Article
- TSAR: a program for automatic resonance assignment using 2D cross-sections of high dimensionality, high-resolution spectra.Journal of biomolecular NMR · 2012Article
- The J-UNIO protocol for automated protein structure determination by NMR in solution.Journal of biomolecular NMR · 2012Article
- Solution NMR of a 463-residue phosphohexomutase: domain 4 mobility, substates, and phosphoryl transfer defect.Biochemistry · 2012Article
- Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones.Journal of molecular biology · 2011Article
- AUTOBA: automation of backbone assignment from HN(C)N suite of experiments.Journal of biomolecular NMR · 2011Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Here we describe a new algorithm for automatically determining the mainchain sequential assignment of NMR spectra for proteins. Using only the customary triple resonance experiments, assignments can be quickly found for not only small proteins having rather complete data, but also for large proteins, even when only half the residues can be assigned. The result of the calculation is not the single best assignment according to some criterion, but rather a large number of satisfactory assignments that are summarized in such a way as to help the user identify portions of the sequence that are assigned with confidence, vs. other portions where the assignment has some correlated alternatives. Thus very imperfect initial data can be used to suggest future experiments.
Indexed as
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20232231What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.