Evidence map›Paper›PMID 20232192›Full record

ArticleCurrent topics in microbiology and immunology2010

Perspectives on vaccines against varicella-zoster virus infections.

Anne A Gershon, Michael D Gershon

Open access · greenAbstract read
In one paragraph

Article in Current topics in microbiology and immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
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  6. Review
  7. Article
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  9. Article
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  11. Review
  12. Article
  13. Varicella infection in the Middle East: Prevalence, complications, and vaccination.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Review
  14. Article
  15. Article
  16. Article
  17. Pathogenesis of varicelloviruses in primates.The Journal of pathology · 2015
    Review
  18. Review
  19. Article
  20. Successes and challenges in varicella vaccine.Therapeutic advances in vaccines · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anne A GershonDepartment of Pediatrics, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA. aag1@columbia.edu
Michael D Gershon
Columbia University · US

Funding

VZV in the enteric nervous system: pathogenesis and consequencesR01DK093094 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MICHAEL D GERSHON, Anne A. Gershon · 2011 to 2026
$5.9M
VZ VIRUS: CLINICAL IMPLICATIONS OF IMMUNITYR01AI024021 · NIAID · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SILVERSTEIN, SAUL J · 1986 to 2008
$3.0M
VZV Receptors and Infective MechanismsR01AI027187 · NIAID · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GERSHON, ANNE A. · 1990 to 2007
$2.4M
Varicella Zoster Virus:Clinical Implications of ImmunityR21AI024021 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SILVERSTEIN, SAUL J · 2003 to 2003
$363k
VZV Receptors &Infective MechanismsR21AI027187 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GERSHON, ANNE A. · 2001 to 2001
$327k
NIAID NIH HHS AI24021NIAID NIH HHS AI27187NIAID NIH HHS R01 AI024021NIAID NIH HHS R01 AI027187NIAID NIH HHS R21 AI024021NIAID NIH HHS R21 AI027187NIDDK NIH HHS R01 DK093094
6 · The paper itself

Abstract

Primary infection with varicella-zoster virus (VZV) results in varicella which, in populations where immunization is not used, occurs mostly in children. Varicella is a generalized rash illness with systemic features such as fever and malaise. During varicella, VZV becomes latent in sensory ganglia of the individual, and in 70% it remains asymptomatic for their lifetime. The remaining 30% develop reactivation from latency, resulting in herpes zoster (HZ). HZ usually occurs in persons over the age of 50, and is manifested by a painful unilateral rash that usually lasts about 2 weeks and then may be followed by a chronic pain syndrome called post-herpetic neuralgia (PHN). VZV infections are notoriously more severe in immunocompromised hosts than in healthy individuals. Despite gaps in our understanding of the details of immunity to VZV, successful vaccines have been developed against both varicella and zoster.

Indexed as

ChickenpoxHerpesvirus 3, HumanHerpesvirus VaccinesHerpes ZosterHumansVaccinationHerpesvirus Vaccines

Identifiers

PMID20232192
PMCPMC5391036
OpenAlexW2176419762

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.