Evidence map›Paper›PMID 20230309›Full record

ReviewExpert opinion on therapeutic patents2010

Novel technologies for the prevention and treatment of dental caries: a patent survey.

Fu Chen, Dong Wang

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on therapeutic patents, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Caries Café: A Method for Consolidating and Co-Constructing Knowledge of Caries.European journal of dental education : official journal of the Association for Dental Education in Europe · 2026
    Article
  4. Review
  5. Review
  6. Synergistic pairing ofJournal of oral microbiology · 2026
    Article
  7. Differential susceptibility of Streptococcus dentisani to dental surfaces: An atomic force microscopy study.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  8. Article
  9. Beyond antibiotics: advances in photothermal strategies for oral infections.Frontiers in bioengineering and biotechnology · 2025
    Review
  10. Article
  11. Article
  12. Application of a Caries Treatment Difficulty Assessment System in Dental Caries Management.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Thermophilin 110 inhibits growth and biofilm formation ofBiotechnology reports (Amsterdam, Netherlands) · 2021
    Article
  17. [Effects of antimicrobial peptide GH12 on the morphology and composition of cariogenic three-species biofilm].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fu ChenUniversity of Nebraska Medical Center, College of Pharmacy, Department of Pharmaceutical Sciences, COP 3026, Omaha, NE 68198-6025, USA.
Dong Wang
University of Nebraska Medical Center · US

Funding

Macromolecular Therapy for Improved Treatment of Rheumatoid ArthritisR01AR053325 · NIAMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WANG, DONG · 2007 to 2009
$673k
NIAMS NIH HHS AR053325NIAMS NIH HHS R01 AR053325
6 · The paper itself

Abstract

importance of the fieldDental caries is one of the most common preventable childhood diseases; people are susceptible to this ailment throughout their lifetime. In the US, 90% of late adolescents and young adults have dental caries, while 94% of all dentate adults had evidence of treated or untreated coronal caries. Dental caries is often not self-limiting and without proper care can progress until the tooth is destroyed. AREAS COVERED IN THIS REVIEW: In this paper, the etiology of dental caries is briefly introduced. It is followed by a thorough review of patents and literatures on the recent development of various novel technologies for the prevention and treatment of dental caries. WHAT THE READER WILL GAIN: Recent advances in anti-plaque agents, including chemoprophylactic agents, antimicrobial peptides, vaccines, probiotics/replacement therapy and sugar substitutes, and remineralization agents including fluorides and casein phosphopeptides are analyzed. TAKE HOME MASSAGE: Both the discovery of new anti-caries agents and the development of dentotropic delivery systems will be the future focus of this research field.

Indexed as

AdolescentAdultAnimalsDental CariesDental PlaqueDrug Delivery SystemsDrug DesignHumansPatents as TopicTooth DemineralizationTooth RemineralizationYoung Adult

Identifiers

PMID20230309
PMCPMC2857592
OpenAlexW2137659824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.