ArticleEuropean journal of nutrition2010
Association of dietary AGEs with circulating AGEs, glycated LDL, IL-1α and MCP-1 levels in type 2 diabetic patients.
Article in European journal of nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Comparative evaluation of oxidative stress biomarkers F2-isoprostanes and 8-OHdG in Parkinson's disease and Type 2 Diabetes Mellitus: a systematic review and meta-analysis of human studies.Annals of medicine · 2026Pooled it
- Chemokines in Prediabetes and Type 2 Diabetes: A Meta-Analysis.Frontiers in immunology · 2021Pooled it
- Classifying oxidative stress by FRedox biology · 2017Pooled it
- Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review.European journal of clinical nutrition · 2013Pooled it
- Comparison of Metabolic and Hormonal Profiles between Low-Advanced Glycation End Products (AGEs) and Standard AGEs-Containing Weight-Loss Diets in Overweight Phenotype-A PCOS Patients: A Randomized Clinical Trial.Reproductive sciences (Thousand Oaks, Calif.) · 2025Trial
- Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease.Clinical journal of the American Society of Nephrology : CJASN · 2012Trial
- Increased skin autofluorescence predicts future cancer development.BMC cancer · 2025Article
- Reference values and biological factors influencing skin autofluorescence.Frontiers in endocrinology · 2025Article
- A Close Relationship Between Ultra-Processed Foods and Adiposity in Adults in Southern Italy.Nutrients · 2024Article
- Ultraprocessed foods and chronic kidney disease-double trouble.Clinical kidney journal · 2023Review
- Receptor for the Advanced Glycation End Products (International journal of molecular sciences · 2023Review
- The Role of Advanced Glycation End Products on Dyslipidemia.Metabolites · 2023Review
- A non-invasive risk score including skin autofluorescence predicts diabetes risk in the general population.Scientific reports · 2022Article
- Advanced Glycation End Products (AGEs) and Chronic Kidney Disease: Does the Modern Diet AGE the Kidney?Nutrients · 2022Review
- Food-Related Carbonyl Stress in Cardiometabolic and Cancer Risk Linked to Unhealthy Modern Diet.Nutrients · 2022Review
- Fluorescent advanced glycation end products in type 2 diabetes and its association with diabetes duration, hemoglobin A1c, and diabetic complications.Frontiers in nutrition · 2022Article
- CUPRAC-Reactive Advanced Glycation End Products as Prognostic Markers of Human Acute Myocardial Infarction.Antioxidants (Basel, Switzerland) · 2021Article
- Intake of dietary advanced glycation end products influences inflammatory markers, immune phenotypes, and antiradical capacity of healthy elderly in a little-studied population.Food science & nutrition · 2020Article
- Review
- The role of phosphatidylserine recognition receptors in multiple biological functions.Cellular & molecular biology letters · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe association of dietary advanced glycation endproducts (AGEs) intake with the oxidative and inflammatory status in type 2 diabetic patients was examined.
methodsSeventy-four healthy controls, 50 low AGEs intake and 68 high AGEs intake type 2 diabetic patients were requested to complete a 7-day dietary record. Blood levels of several oxidative and inflammatory biomarkers were determined.
resultsDiabetic patients with high AGEs intake had significantly elevated plasma levels of AGEs, HbA1c, low-density lipoprotein (LDL), LDL-cholesterol and glycated LDL than low AGEs intake patients and controls (P < 0.05). These high AGEs intake patients also had significantly increased plasma levels of 8-isoprostane, interleukin (IL)-1α, tumor necrosis factor-α, monocyte chemoattractant protein (MCP)-1 and lower superoxide dismutase (SOD) activity than low AGEs intake patients (P < 0.05). Correlation coefficients of dietary AGEs versus plasma AGEs, HbA1c, 8-isoprostane, IL-1α and MCP-1 were >0.6; but the correlation coefficient of dietary AGEs versus plasma SOD activity was <-0.6.
conclusionIncreasing dietary AGEs intake might enrich circulating AGE level and contribute to oxidative and inflammatory progression under diabetic condition. The circulating 8-isoprostane, IL-1α and MCP-1 levels and SOD activity might be appropriate biomarkers used to evaluate dietary AGEs-associated oxidative and inflammatory stress.
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Registered trials
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