Evidence map›Paper›PMID 20229037›Full record

ArticleMycopathologia2010

Response to oxidative stress in eight pathogenic yeast species of the genus Candida.

Maxwel Adriano Abegg, Paulo Vinicius Gil Alabarse, Anderson Casanova, Jaqueline Hoscheid, Tiago Boeira Salomon, Fernanda Schäfer Hackenhaar, Tássia Machado Medeiros, Mara Silveira Benfato

Abstract read
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Article in Mycopathologia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maxwel Adriano AbeggPrograma de Pós-Graduação em Biologia Celular e Molecular (PPGBCM), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Paulo Vinicius Gil Alabarse
Anderson Casanova
Jaqueline Hoscheid
Tiago Boeira Salomon
Fernanda Schäfer Hackenhaar
Tássia Machado Medeiros
Mara Silveira Benfato
Universidade Federal do Rio Grande do Sul · BRUniversidade Paranaense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the course of an infection, the formation of reactive oxygen species by phagocytes and the antioxidant defense mechanisms of microorganisms play a crucial role in pathogenesis. In this study, isolates representing 8 pathogenic Candida species-Candida albicans, Candida dubliniensis, Candida famata, Candida glabrata, Candida guilliermondii, Candida krusei, Candida parapsilosis and Candida tropicalis-were compared with regard to their resistance to oxidative stress in vitro. We evaluated degree of resistance, induction of oxidative damage, capacity to adapt, and induction of antioxidant enzymes. The species showed variable sensitivity to oxidative attack. C. albicans, C. glabrata, and C. krusei were more resistant to oxidative stress under the conditions tested; C. parapsilosis and C. tropicalis presented medium resistance; and C. dubliniensis, C. famata, and C. guilliermondii were more sensitive. The overall greater resistance to oxidative stress of C. albicans and C. glabrata may provide an advantage to these species, which are the major causative agents of candidiasis.

Indexed as

Oxidative StressStress, PhysiologicalAntioxidantsCandidaHumansMicrobial ViabilityOxidantsReactive Oxygen SpeciesAntioxidantsOxidantsReactive Oxygen Species

Identifiers

PMID20229037
OpenAlexW2151233690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.