ReviewAging2010
Aging: Dial M for Mitochondria.
Review in Aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Partial reduction of the mitochondrial lipoyltransferase LipT2 promotes longevity and redox remodeling in Drosophila.Biogerontology · 2026Article
- Comparative Metabolomic Study ofInternational journal of molecular sciences · 2021Article
- Observational
- The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress.Nanomedicine : nanotechnology, biology, and medicine · 2020Article
- GRSF1 is an age-related regulator of senescence.Scientific reports · 2019Article
- Autophagy and Longevity.Molecules and cells · 2018Review
- Article
- Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera).Experimental gerontology · 2014Article
- Article
- Article
- Review
- dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster.Cell cycle (Georgetown, Tex.) · 2012Article
- RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice.Aging · 2012Article
- Autophagy - An Emerging Anti-Aging Mechanism.Journal of clinical & experimental pathology · 2012Article
- Unmasking a temperature-dependent effect of the P. anserina i-AAA protease on aging and development.Cell cycle (Georgetown, Tex.) · 2011Article
- Article
- TOR and ageing: a complex pathway for a complex process.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2011Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A major goal of aging research is to identify interventions that prolong lifespan in distantly related organisms. In recent years, genetic studies in both nematodes and rodents have reported that moderate inactivation of genes important for mitochondrial electron transport chain (ETC) function can promote longevity. We performed an RNAi screen to probe the role of ETC components in modulating lifespan in the fruit fly Drosophila melanogaster. In this Research Perspective, we discuss our findings and how they may relate to similar studies in worms and mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.