ArticleTetrahedron2010
Scalable and efficient synthesis of the mycolactone core.
Article in Tetrahedron, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Review
- The chemistry and biology of mycolactones.Beilstein journal of organic chemistry · 2017Review
- Short Convergent Synthesis of the Mycolactone Core Through Lithiation-Borylation Homologations.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015Article
- Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans.PLoS neglected tropical diseases · 2013Article
- Chemistry of mycolactones, the causative toxins of Buruli ulcer.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Highly stereoselective total synthesis of fully hydroxy-protected mycolactones A and B and their stereoisomerization upon deprotection.Chemistry (Weinheim an der Bergstrasse, Germany) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A highly efficient, scalable, and stereoselective synthesis of the mycolactone core is reported. The synthesis consists of 14 longest linear steps, with 19% overall yield.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.