Evidence map›Paper›PMID 20228870›Full record

ArticleExpert review of endocrinology & metabolism2009

Tumor-induced osteomalacia.

Emily G Farrow, Kenneth E White

Open access · greenAbstract read
In one paragraph

Article in Expert review of endocrinology & metabolism, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Oncogenic osteomalacia secondary to glomus tumor.Endocrinology, diabetes & metabolism case reports · 2021
    Article
  7. Article
  8. Diagnostic performance and impact on patient management ofEuropean journal of nuclear medicine and molecular imaging · 2018
    Article
  9. Tumor-induced osteomalacia: experience from a South American academic center.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
  10. Article
  11. Review
  12. Article
  13. Rickets: Part II.Pediatric radiology · 2013
    Review
  14. The skeleton as an endocrine organ.Nature reviews. Rheumatology · 2012
    Review
  15. Article
  16. Height loss and generalized pain in a 35-year-old man.The American journal of medicine · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Emily G FarrowDepartment of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
Kenneth E White
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

FGF-23 REGULATION OF PHOSPHATE HOMEOSTASISR01DK063934 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WHITE, KENNETH E · 2003 to 2015
$3.8M
NIDDK NIH HHS R01 DK063934
6 · The paper itself

Abstract

Tumor-induced osteomalacia (TIO) is an acquired disorder of isolated renal phosphate wasting associated with tumors, typically of mesenchymal origin. Patients with TIO share similar biochemical and skeletal phenotypes with patients who have autosomal dominant hypophosphatemic rickets (ADHR) and X-linked hypophosphatemia. The study of TIO introduced the idea of the existence of circulating factors, referred to as 'phosphatonins', produced by the tumor, which act upon the kidney to reduce phosphate reabsorption. Although several factors have been identified, the phosphatonin FGF-23, also identified as the causative factor in ADHR, is currently the best characterized of these factors relative to phosphate handling. This review describes the importance of TIO in understanding phosphate homeostasis in the context of new endocrine interactions between the skeleton and the kidney.

Identifiers

PMID20228870
PMCPMC2835164
OpenAlexW2009846425

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.