Evidence map›Paper›PMID 20226596›Full record

ArticleVeterinary parasitology2010

Molecular characterization of Sarcocystis neurona strains from opossums (Didelphis virginiana) and intermediate hosts from Central California.

Daniel Rejmanek, Melissa A Miller, Michael E Grigg, Paul R Crosbie, Patricia A Conrad

Open access · greenAbstract read
In one paragraph

Article in Veterinary parasitology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Parasite genotype is a risk factor forInternational journal for parasitology. Parasites and wildlife · 2026
    Article
  3. Article
  4. A global checklist of the parasites of the harbor porpoiseInternational journal for parasitology. Parasites and wildlife · 2021
    Article
  5. Article
  6. Detection and characterization of diverse coccidian protozoa shed by California sea lions.International journal for parasitology. Parasites and wildlife · 2016
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Daniel RejmanekDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. drejmanek@ucdavis.edu
Melissa A Miller
Michael E Grigg
Paul R Crosbie
Patricia A Conrad
University of California, Davis · USCalifornia Department of Fish and Wildlife · USCalifornia State University, Fresno · USNational Institutes of Health · US

Funding

Toxoplasma Population GeneticsZIAAI001018 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GRIGG, MICHAEL · 2009 to 2025
$11.3M
Toxoplasma Surface Antigens and ImmunityZIAAI001017 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GRIGG, MICHAEL · 2009 to 2025
$9.9M
Toxoplasma Surface Antigens and ImmunityZ01AI001017 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI GRIGG, MICHAEL · 2007 to 2008
$801k
Intramural NIH HHS Z01 AI001017
6 · The paper itself

Abstract

Sarcocystis neurona is a significant cause of neurological disease in horses and other animals, including the threatened Southern sea otter (Enhydra lutris nereis). Opossums (Didelphis virginiana), the only known definitive hosts for S. neurona in North America, are an introduced species in California. S. neurona DNA isolated from sporocysts and/or infected tissues of 10 opossums, 6 horses, 1 cat, 23 Southern sea otters, and 1 harbor porpoise (Phocoena phocoena) with natural infections was analyzed based on 15 genetic markers, including the first internal transcribed spacer (ITS-1) region; the 25/396 marker; S. neurona surface antigen genes (snSAGs) 2, 3, and 4; and 10 different microsatellites. Based on phylogenetic analysis, most of the S. neurona strains segregated into three genetically distinct groups. Additionally, fifteen S. neurona samples from opossums and several intermediate hosts, including sea otters and horses, were found to be genetically identical across all 15 genetic markers, indicating that fatal encephalitis in Southern sea otters and equine protozoal myeloencephalitis (EPM) in horses is strongly linked to S. neurona sporocysts shed by opossums.

Indexed as

PhylogenyAmino Acid SequenceAnimalsAntigens, ProtozoanBase SequenceCaliforniaConservation of Natural ResourcesDNA, ProtozoanDNA, Ribosomal SpacerMicrosatellite RepeatsMolecular Sequence DataOpossumsOttersPolymerase Chain ReactionPolymorphism, GeneticSarcocystisAntigens, ProtozoanDNA, ProtozoanDNA, Ribosomal Spacer

Identifiers

PMID20226596
PMCPMC4878691
OpenAlexW2046021758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.