ReviewSeminars in thoracic and cardiovascular surgery2009
Image-guided sentinel lymph node mapping and nanotechnology-based nodal treatment in lung cancer using invisible near-infrared fluorescent light.
Review in Seminars in thoracic and cardiovascular surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Diagnostic accuracy of sentinel lymph node biopsy using indocyanine green in lung cancer: a systematic review and meta-analysis.General thoracic and cardiovascular surgery · 2020Pooled it
- Pulmonary Endogenous Fluorescence Allows the Distinction of Primary Lung Cancer from the Perilesional Lung Parenchyma.PloS one · 2015Trial
- A novel system for analyzing indocyanine green (ICG) fluorescence spectra enables deeper lung tumor localization during thoracoscopic surgery.Journal of thoracic disease · 2022Article
- Recent Developments of ICG-Guided Sentinel Lymph Node Mapping in Oral Cancer.Diagnostics (Basel, Switzerland) · 2021Review
- Small Molecules for Multi-Wavelength Near-Infrared Fluorescent Mapping of Regional and Sentinel Lymph Nodes in Colorectal Cancer Staging.Frontiers in oncology · 2020Article
- mRhubarb: Engineering of monomeric, red-shifted, and brighter variants of iRFP using structure-guided multi-site mutagenesis.Scientific reports · 2019Article
- Real-Time Fluorescence Imaging in Thoracic Surgery.The Korean journal of thoracic and cardiovascular surgery · 2019Article
- Deciding to trust, coming to believe: sentinel lymph node assessment in lung cancer.Journal of thoracic disease · 2018Article
- Editorial on "Long-term outcomes after near-infrared sentinel lymph node mapping in non-small cell lung cancer".Journal of thoracic disease · 2018Article
- Genetic Assembly of Double-Layered Fluorescent Protein Nanoparticles for Cancer Targeting and Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017Article
- Clear-cut observation of clearance of sustainable upconverting nanoparticles from lymphatic system of small living mice.Scientific reports · 2016Article
- From Diagnosis to Treatment: Clinical Applications of Nanotechnology in Thoracic Surgery.Thoracic surgery clinics · 2016Review
- Intraoperative imaging identifies thymoma margins following neoadjuvant chemotherapy.Oncotarget · 2016Article
- Difficulty of predicting the presence of lymph node metastases in patients with clinical early stage gastric cancer: a case control study.BMC cancer · 2015Article
- Management of nodal disease from colon cancer in the laparoscopic era.International journal of colorectal disease · 2015Review
- Advances in the application of nanotechnology in the diagnosis and treatment of gastrointestinal tumors.Molecular and clinical oncology · 2015Article
- Article
- Light-emitting diode-based multiwavelength diffuse optical tomography system guided by ultrasound.Journal of biomedical optics · 2014Article
- A "schizophotonic" all-in-one nanoparticle coating for multiplexed SE(R)RS biomedical imaging.Angewandte Chemie (International ed. in English) · 2014Article
- Impacts of quantum dots in molecular detection and bioimaging of cancer.BioImpacts : BI · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Current methods for sentinel lymph node (SLN) mapping and nodal treatment in lung cancer remain inadequate for routine clinical use. In this study, we discuss the potential for using the combination of invisible near-infrared (NIR) fluorescent light and nanotechnology for these applications. NIR fluorescence imaging has recently received significant attention for in vivo imaging applications because of its low tissue autofluorescence, high photon penetration into living tissue, and high signal-to-background ratio. Our large animal in vivo studies have been able to successfully identify SLNs in lung tissue, and several clinical studies have examined the use of NIR fluorescence imaging systems for SLN mapping in breast and gastric cancer. Promising new nanoparticle technologies, when combined with NIR fluorescence imaging, offer the potential for image-guided treatment of lymph nodes at high risk for tumor recurrence. This review provides a theoretic and empiric framework for developing the next generation of diagnostic and therapeutic agents for lung cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.