ArticleThe Journal of infectious diseases2010
Challenges for rapid molecular HIV diagnostics.
Article in The Journal of infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Clinical versus rapid molecular HIV diagnosis in hospitalized African infants: a randomized controlled trial simulating point-of-care infant testing.Journal of acquired immune deficiency syndromes (1999) · 2014Trial
- Development and evaluation of a high-sensitivity RT-PCR lateral flow assay for early detection of HIV-1 infection.Heliyon · 2024Article
- Label-free detection of synthetic, full genomic length HIV-1 RNA at the few-copy level.Sensors and actuators. B, Chemical · 2023Article
- False reactive HIV-1 diagnostic test results in an individual from Kenya on multiple testing platforms-A case report.IDCases · 2021Article
- Evolution of Biochip Technology: A Review from Lab-on-a-Chip to Organ-on-a-Chip.Micromachines · 2020Review
- HIV Detection via a Carbon Nanotube RNA Sensor.ACS sensors · 2019Article
- Field evaluation of HIV point-of-care testing for early infant diagnosis in Cape Town, South Africa.PloS one · 2017Article
- Identification of HIV Mutation as Diagnostic Biomarker through Next Generation Sequencing.Journal of clinical and diagnostic research : JCDR · 2016Article
- Viral glycoproteins: biological role and application in diagnosis.Virusdisease · 2016Review
- Barriers to Implementation of Rapid and Point-of-Care Tests for Human Immunodeficiency Virus Infection: Findings From a Systematic Review (1996-2014).Point of care · 2015Article
- Detection of Acute HIV-1 Infection by RT-LAMP.PloS one · 2015Article
- Point of Care Technologies for HIV.AIDS research and treatment · 2014Review
- Perspectives on introduction and implementation of new point-of-care diagnostic tests.The Journal of infectious diseases · 2012Article
- Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis.The Journal of infectious diseases · 2012Article
- Testing for acute HIV infection: implications for treatment as prevention.Current opinion in HIV and AIDS · 2012Review
- Isothermal amplification using a chemical heating device for point-of-care detection of HIV-1.PloS one · 2012Article
- HIV testing in developing countries: what is required?The Indian journal of medical research · 2011Review
- Temporal changes in HCV genotype distribution in three different high risk populations in San Francisco, California.BMC infectious diseases · 2011Article
- Cost analysis of centralized viral load testing for antiretroviral therapy monitoring in Nicaragua, a low-HIV prevalence, low-resource setting.Journal of the International AIDS Society · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The introduction of serological point-of-care assays 10 years ago dramatically changed the way that human immunodeficiency virus (HIV) infection was identified and diagnosed. Testing at the point of care has lead to a dramatic increase in the number of individuals who are screened and, most importantly, receive their HIV test result. As the AIDS epidemic continues to mature and scientific advances in prevention and treatment are evaluated and implemented, there is a need to identify acute (viremic preseroconversion) infections and to discriminate "window phase" infections from those that are serologically positive, especially in resource-limited settings, where the majority of vulnerable populations reside and where the incidence of HIV infection is highest. Rapid testing methods are now at a crossroads. There is opportunity to implement and evaluate the incremental diagnostic usefulness of new test modalities that are based on sophisticated molecular diagnostic technologies and that can be performed in settings where laboratory infrastructure is minimal. The way forward requires sound scientific judgment and an ability to further develop and implement these tests despite a variety of technical, social, and operational hurdles, to declare success.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.