ArticleDermato-endocrinology2009
Epidermal surface lipids.
Article in Dermato-endocrinology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
130 citing papers in PubMed, 2 syntheses or guidelines pooled it, 319 citations in OpenAlex.
- Pooled it
- Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways.BMC medical genomics · 2015Pooled it
- Clinical Study of Intradermal Injection of Non-Crosslinked Sodium Hyaluronate Combined With Human Epidermal Growth Factor in the Treatment of Skin Barrier Injury in Plateau Area.Journal of cosmetic dermatology · 2025Trial
- Trial
- Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study.Nutrients · 2020Trial
- Damage to sebaceous gland and the efficacy of moisturizer after whole breast radiotherapy: a randomized controlled trial.BMC cancer · 2019Trial
- Surface characterization of curcumin-visualized latent fingerprints on metal surfaces.Analytical and bioanalytical chemistry · 2026Article
- Scalp Cooling as a Biopsychosocial Intervention in Patients Receiving Highly Alopecia-Inducing Chemotherapy: Prospective Single-Arm Study.JMIR cancer · 2026Article
- Review
- Differential pathogenic and commensal response ofJournal of bacteriology · 2026Article
- The Beauty Health Index (BHI): A Proposed Framework for Quantifying Facial Aesthetic Health.Cureus · 2026Review
- Towards an attract-and-kill strategy for sustainable tick control: combined effects of Metarhizium anisopliae and phytochemical attractants from Senna didymobotrya against Amblyomma variegatum and Rhipicephalus appendiculatus.Experimental & applied acarology · 2026Article
- The Acari Hypothesis, VIII: the human apocrine-mammary-microbiota axis andFrontiers in microbiology · 2026Article
- From sebocytes to skin engineering human sebaceous organoids within a reconstructed dermal matrix.Frontiers in toxicology · 2026Article
- Evaluation of Skin Penetration of Fluorescent Dissolved Formulations Using Confocal Laser Scanning Microscopy.Pharmaceutics · 2025Article
- Locally ordered junctions govern diffusion in triglycerides: insights from molecular dynamics simulations.RSC advances · 2025Article
- Lipidomic profiling of skin surface lipids in a cohort of Chinese patients with rosacea.Scientific reports · 2025Article
- Strongyloides species exhibit distinct behaviors on the skin of different mammals.BMC infectious diseases · 2025Article
- Establishing anmSphere · 2025Article
- The Utility of Fourier Transform Infrared Spectroscopy (FTIR) for Detecting Exercise-Induced Changes in the Human Hand Epidermis.Journal of biophotonics · 2025Article
70 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A layer of lipids, which are of both sebaceous and keratinocyte origin, covers the surface of the skin. The apparent composition of surface lipids varies depending on the selected method of sampling. Lipids produced by the epidermal cells are an insignificant fraction of the total extractable surface lipid on areas rich in sebaceous glands. Due to the holocrine activity of the sebaceous gland, its product of secretion (sebum) is eventually released to the surface of the skin and coats the fur as well. Lipids of epidermal origin fill the spaces between the cells, like mortar or cement. The sebaceous lipids are primarily non polar lipids as triglycerides, wax esters and squalene, while epidermal lipids are a mixture of ceramides, free fatty acids and cholesterol. The composition of the sebaceous lipids is unique and intriguing and elevated sebum excretion is a major factor involved in the pathophysiology of acne. Recent studies have elucidated the roles that epidermal surface lipids have on normal skin functions and acne.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.