Evidence map›Paper›PMID 20223738›Full record

ArticleInternational journal of bioinformatics research and applications2010

Strategies for enhanced annotation of a microarray probe set.

Tushun R Powers, Selene M Virk, Elba E Serrano

Abstract read
In one paragraph

Article in International journal of bioinformatics research and applications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tushun R PowersDepartment of Biology, New Mexico State University, Las Cruces, NM 88003, USA. tupowers@nmsu.edu
Selene M Virk
Elba E Serrano
New Mexico State University · US

Funding

Systems Biology of Cell Decision ProcessesP50GM068762 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YAFFE, MICHAEL B · 2003 to 2012
$32.3M
Translational Control in the Hepatitis C VirusS06GM008136 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI KUEHN, GLENN D · 1989 to 2011
$23.2M
RISE PROGRAM AT NEW MEXICO STATE UNIVERSITYR25GM061222 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI HOUSTON, JESSICA PEREA, REDDI, LAKSHMI · 2000 to 2022
$21.3M
Development of the Acoustico-Vestibular SystemR01DC003292 · NIDCD · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI SERRANO, ELBA E · 2004 to 2005
$492k
DEVELOPMENT OF THE XENOPUS ACOUSTICO-VESTIBULAR SYSTEMR29DC003292 · NIDCD · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI SERRANO, ELBA E · 1998 to 2002
$318k
NIDCD NIH HHS DC003292NIDCD NIH HHS R01 DC003292NIDCD NIH HHS R29 DC003292NIGMS NIH HHS GM008136NIGMS NIH HHS P50 GM068762NIGMS NIH HHS P50GM068762NIGMS NIH HHS R25 GM061222NIGMS NIH HHS S06 GM008136
6 · The paper itself

Abstract

We aim to determine the biological relevance of genes identified through microarray-mediated transcriptional profiling of Xenopus sensory organs and brain. Difficulties with genetic data analysis arise because of limitations in probe set annotation and the lack of a universal gene nomenclature. To overcome these impediments, we used sequence based and semantic linking methods in combination with computational approaches to augment probe set annotation on a commercially available microarray. Our curation efforts enabled linkage of probe sets and expression data to public databases, increased the biological significance of our microarray data, and assisted with the tentative identification of unidentified probe sets.

Indexed as

Computational BiologyDatabases, FactualDatabases, GeneticOligonucleotide Array Sequence AnalysisProteomeProteome

Identifiers

PMID20223738
PMCPMC2955980
OpenAlexW2106969335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.