Evidence map›Paper›PMID 20223598›Full record

Trial reportPsychoneuroendocrinology2010

Behavioral adjustment in a community sample of boys: links with basal and stress-induced salivary cortisol concentrations.

Audrey R Tyrka, Megan M Kelly, Julia A Graber, Laura DeRose, Janet K Lee, Michelle P Warren, Jeanne Brooks-Gunn

Abstract readClinical Trial
In one paragraph

Trial report in Psychoneuroendocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Audrey R TyrkaButler Hospital, Providence, RI 02906, USA. Audrey_Tyrka@Brown.edu
Megan M Kelly
Julia A Graber
Laura DeRose
Janet K Lee
Michelle P Warren
Jeanne Brooks-Gunn

Funding

Infrastructure for Population Research at PrincetonR24HD047879 · NICHD · PRINCETON UNIVERSITY · PI MASSEY, DOUGLAS S · 2004 to 2013
$7.3M
CONTEXTUAL, BEHAVIORAL &PHYSIOLOGICAL PROCESSES IN BOYSR01MH056557 · NIMH · COLUMBIA UNIVERSITY TEACHERS COLLEGE · PI BROOKS-GUNN, JEANNE · 1999 to 2003
$1.1M
Risk for Depression Stress and Neuroendocrine FunctionK23MH067947 · NIMH · BUTLER HOSPITAL (PROVIDENCE, RI) · PI TYRKA, AUDREY · 2004 to 2008
$905k
NICHD NIH HHS R24 HD047879NIMH NIH HHS 1 K23 MH067947NIMH NIH HHS K23 MH067947NIMH NIH HHS MH56557NIMH NIH HHS R01 MH056557
6 · The paper itself

Abstract

Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been observed in association with internalizing symptoms and is thought to be involved in the pathogenesis of depression and some anxiety disorders. This study examined basal and stress-induced cortisol concentrations in relation to internalizing and externalizing symptoms in a racially mixed community sample of 102 8-11-year-old boys. Afternoon basal cortisol concentrations were positively correlated with measures of internalizing behavior problems, social problems, and emotionality. Greater change in cortisol across a home-visit challenge task was also significantly associated with internalizing behaviors and social problems, as well as attention and thought problems. The implications of these findings and how they may relate to the pathogenesis of emotional and behavioral problems are discussed.

Indexed as

Social AdjustmentAdaptation, PsychologicalChildChild BehaviorCircadian RhythmHouse CallsHumansHydrocortisoneMaleOsmolar ConcentrationResidence CharacteristicsSalivaStress, PsychologicalHydrocortisone

Identifiers

PMID20223598
PMCPMC2922420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.