Evidence map›Paper›PMID 20223474›Full record

ArticleThe Journal of pediatrics2010

Children with chronic illness return to their baseline functional status after organ dysfunction on the first day of admission in the pediatric intensive care unit.

Katri V Typpo, Nancy J Petersen, Laura A Petersen, M Michele Mariscalco

Abstract readMulticenter Study
In one paragraph

Article in The Journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Outcomes of Day 1 Multiple Organ Dysfunction Syndrome in the PICU.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019
    Observational
  5. Characteristics and Outcomes of Critical Illness in Children With Feeding and Respiratory Technology Dependence.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019
    Article
  6. Article
  7. Article
  8. Epidemiology and Outcomes of Pediatric Multiple Organ Dysfunction Syndrome.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2017
    Review
  9. Epidemiology of Pediatric Critical Illness in a Population-Based Birth Cohort in Olmsted County, MN.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2017
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katri V TyppoSection of Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Nancy J Petersen
Laura A Petersen
M Michele Mariscalco

Funding

RESEARCH TRAINING IN PEDIATRIC CRITICAL CARE MEDICINET32HL007939 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI SHEKERDEMIAN, LARA SEVANNE · 2002 to 2012
$1.4M
NHLBI NIH HHS T32 HL007939NHLBI NIH HHS T32HL007939
6 · The paper itself

Abstract

objectiveTo determine chronic illness outcomes after admission with multiple organ dysfunction syndrome (MODS) for patients in the pediatric intensive care unit (PICU). STUDY

designWe evaluated consecutive PICU admissions from 35 US children's hospitals from January 2004-December 2005 in the virtual PICU Performance System database. We excluded hospitals with >10% missing values for MODS variables and patients<1 month or>18 years of age. MODS was identified by laboratory and vital sign values from day of admission with International Pediatric Sepsis Consensus Conference criteria. Chronic illness was identified by secondary diagnoses, classified by modified Delphi method. We evaluated functional outcomes with pediatric overall performance category and pediatric cerebral performance category scores from PICU admission and discharge.

resultsOf 44 693 admissions, 52.1% had a chronic diagnosis. Chronic diagnoses increased MODS at PICU admission (24.6% vs 12.0%, P<.001) and mortality rates (3.7% vs 1.9%, P<.001). Patients with a chronic diagnosis had similar changes in pediatric overall performance category and pediatric cerebral performance category scores from PICU admission to discharge as previously healthy children. However, outcome in different chronic diagnosis categories was variable.

conclusionsChronic illness increased MODS incidence at PICU admission and impacted all-cause PICU mortality rates. Although, in aggregate, children who survive return to baseline functional status, this varies by chronic illness category.

Indexed as

Intensive Care Units, PediatricChildChronic DiseaseFemaleHumansIncidenceMaleMultiple Organ FailureOutcome and Process Assessment, Health CarePatient AdmissionPatient DischargePrognosisRisk FactorsSeverity of Illness IndexTime FactorsUnited States

Identifiers

PMID20223474
PMCPMC4406357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.