Evidence map›Paper›PMID 20221763›Full record

ArticleDer Pathologe2010

[Atypical lipomatous tumors of the stomach. Clinical, morphological and molecular findings].

C Kuhnen, T Mentzel, W Haarmann, U Schwegler, R Sciot, M Debiec-Rychter

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Der Pathologe, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

C KuhnenInstitut für Pathologie am Clemenshospital, Medical Center, Düesbergweg 128, 48153 Münster. kuhnen@patho-muenster.de
T Mentzel
W Haarmann
U Schwegler
R Sciot
M Debiec-Rychter
KU Leuven · BEMartin-Luther-Krankenhaus · DEClemenshospital Münster · DEDermatopathologie Friedrichshafen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two cases of primary gastric atypical lipomatous tumors (ALT) are presented. In case No.1, a 7x4x3 cm submucosal ALT (lipoma-like subtype) of the antrum/pyloric region in a 60-year-old woman was completely resected. Using interphase dual-color-FISH, MDM2- and CDK4 amplifications could be detected in distinguished amplicons. The patient was continuously free of disease after 56 months. In case No. 2, a 3.5 cm (in diameter) submucosal ALT (lipoma-like subtype) of the gastric body in a 56-year-old woman was completely resected. FISH revealed MDM2 amplification while the CDK4 gene remained in diploid copies. This patient was continuously free of disease after 36 months. The morphologic and molecular biological findings of this rare primary gastric mesenchymal tumor are discussed in comparison with the corresponding soft tissue lesions.

Indexed as

Cyclin-Dependent Kinase 4Diagnosis, DifferentialFemaleGastroscopyGene AmplificationHumansImmunohistochemistryIn Situ Hybridization, FluorescenceLipomaMiddle AgedNeoplasms, Adipose TissueProto-Oncogene Proteins c-mdm2Stomach NeoplasmsTreatment OutcomeCyclin-Dependent Kinase 4MDM2 protein, humanProto-Oncogene Proteins c-mdm2

Identifiers

PMID20221763
OpenAlexW1531747201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.