Evidence map›Paper›PMID 20221560›Full record

ArticleLab on a chip2010

Pressure-driven laminar flow switching for rapid exchange of solution environment around surface adhered biological particles.

Peter B Allen, Graham Milne, Byron R Doepker, Daniel T Chiu

Abstract read
In one paragraph

Article in Lab on a chip, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Controlling mass transport in microfluidic devices.Annual review of analytical chemistry (Palo Alto, Calif.) · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter B AllenDept. of Chemistry, University of Washington, Seattle, WA 98195, USA.
Graham Milne
Byron R Doepker
Daniel T Chiu

Funding

High-Resolution Analysis of Synaptic ProteinsR01NS052637 · NINDS · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T · 2005 to 2013
$3.2M
Single-Molecule Studies of Synaptic VesiclesR01NS062725 · NINDS · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T · 2008 to 2011
$1.3M
NINDS NIH HHS NS 052637NINDS NIH HHS NS062725NINDS NIH HHS R01 NS052637NINDS NIH HHS R01 NS062725
6 · The paper itself

Abstract

This paper describes a technique for rapidly exchanging the solution environment near a surface by displacing laminar flow fluid streams using sudden changes in applied pressure. The method employs off-chip solenoid valves to induce pressure changes, which is important in keeping the microfluidic design simple and the operation of the system robust. The performance of this technique is characterized using simulation and validated with experiments. This technique adds to the microfluidic tool box that is currently available for manipulating the solution environment around biological particles and molecules.

Indexed as

BiopolymersCell AdhesionCell SeparationEquipment DesignEquipment Failure AnalysisFlow Injection AnalysisMicro-Electrical-Mechanical SystemsMicrofluidic Analytical TechniquesParticle SizePressureSolutionsSurface PropertiesBiopolymersSolutions

Identifiers

PMID20221560
PMCPMC2868337

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.