ArticlePloS one2010
Microarrays reveal early transcriptional events during the termination of larval diapause in natural populations of the mosquito, Wyeomyia smithii.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 79 citations in OpenAlex.
- Crosstalk in the cold: host-microbe interactions in insect diapause.Annals of the Entomological Society of America · 2026Review
- Molecular mechanisms and comparative transcriptomics of diapause in two corn rootworm species (Current research in insect science · 2025Article
- Bacterial communities in carnivorous pitcher plants colonize and persist in inquiline mosquitoes.Animal microbiome · 2022Article
- Evolutionary and functional genetics of insect diapause: a call for greater integration.Current opinion in insect science · 2019Review
- Understanding the regulation of overwintering diapause molecular mechanisms in Culex pipiens pallens through comparative proteomics.Scientific reports · 2019Article
- Conceptual framework of the eco-physiological phases of insect diapause development justified by transcriptomic profiling.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Preparing for Winter: The Transcriptomic Response Associated with Different Day Lengths in Drosophila montana.G3 (Bethesda, Md.) · 2016Article
- Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster.BMC genomics · 2016Article
- Characterization of Reproductive Dormancy in MaleFrontiers in physiology · 2016Article
- Comparative Transcriptomics Reveals Key Gene Expression Differences between Diapausing and Non-Diapausing Adults of Culex pipiens.PloS one · 2016Article
- Early transcriptional events linked to induction of diapause revealed by RNAseq in larvae of drosophilid fly, Chymomyza costata.BMC genomics · 2015Article
- Global transcriptional dynamics of diapause induction in non-blood-fed and blood-fed Aedes albopictus.PLoS neglected tropical diseases · 2015Article
- Is a change in juvenile hormone sensitivity involved in range expansion in an invasive beetle?Frontiers in zoology · 2015Article
- RNA-Seq reveals early distinctions and late convergence of gene expression between diapause and quiescence in the Asian tiger mosquito, Aedes albopictus.The Journal of experimental biology · 2013Article
- Deep sequencing reveals complex mechanisms of diapause preparation in the invasive mosquito, Aedes albopictus.Proceedings. Biological sciences · 2013Article
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- Transcriptional response of honey bee larvae infected with the bacterial pathogen Paenibacillus larvae.PloS one · 2013Article
- Article
- A de novo transcriptome of the Asian tiger mosquito, Aedes albopictus, to identify candidate transcripts for diapause preparation.BMC genomics · 2011Article
- Identification of gene expression changes associated with the initiation of diapause in the brain of the cotton bollworm, Helicoverpa armigera.BMC genomics · 2011Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe mosquito Wyeomyia smithii overwinters in a larval diapause that is initiated, maintained and terminated by day length (photoperiod). We use a forward genetic approach to investigate transcriptional events involved in the termination of diapause following exposure to long-days. METHODS/PRINCIPAL
findingsWe incorporate a novel approach that compares two populations that differentially respond to a single day length. We identify 30 transcripts associated with differential response to day length. Most genes with a previously annotated function are consistent with their playing a role in the termination of diapause, in downstream developmental events, or in the transition from potentially oxygen-poor to oxygen-rich environments. One gene emerges from three separate forward genetic screens as a leading candidate for a gene contributing to the photoperiodic timing mechanism itself (photoperiodic switch). We name this gene photoperiodic response gene 1 (ppdrg1). WsPpdrg1 is up-regulated under long-day response conditions, is located under a QTL for critical photoperiod and is associated with critical photoperiod after 25 generations of recombination from a cross between extreme phenotypes.
conclusionsThree independent forward genetic approaches identify WsPpdrg1 as a gene either involved in the photoperiodic switch mechanism or very tightly linked to a gene that is. We conclude that continued forward genetic approaches will be central to understanding not only the molecular basis of photoperiodism and diapause, but also the evolutionary potential of temperate and polar animal populations when confronted with rapid climate change.
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