ArticleDose-response : a publication of International Hormesis Society2010
Hormesis, adaptive epigenetic reorganization, and implications for human health and longevity.
Article in Dose-response : a publication of International Hormesis Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Iron Oxide Nanoparticles with and without Cobalt Functionalization Provoke Changes in the Transcription Profile via Epigenetic Modulation of Enhancer Activity.Nano letters · 2023Article
- Background radiation impacts human longevity and cancer mortality: reconsidering the linear no-threshold paradigm.Biogerontology · 2021Article
- Low-dose ionizing radiation as a hormetin: experimental observations and therapeutic perspective for age-related disorders.Biogerontology · 2021Review
- Ionizing Radiation-Induced Epigenetic Modifications and Their Relevance to Radiation Protection.International journal of molecular sciences · 2020Review
- Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms.Journal of psychiatric research · 2020Article
- Prenatal Malnutrition-Induced Epigenetic Dysregulation as a Risk Factor for Type 2 Diabetes.International journal of genomics · 2019Review
- Developmental Tuning of Epigenetic Clock.Frontiers in genetics · 2018Article
- Non-genomic transmission of longevity between generations: potential mechanisms and evidence across species.Epigenetics & chromatin · 2017Review
- Impacts of Early Life Stress on the Methylome and Transcriptome of Atlantic Salmon.Scientific reports · 2017Article
- Biomarkers of oxidative and nitro-oxidative stress: conventional and novel approaches.British journal of pharmacology · 2017Review
- Radiobiology in Cardiovascular Imaging.JACC. Cardiovascular imaging · 2016Review
- Costs, benefits and redundant mechanisms of adaption to chronic low-dose stress in yeast.Cell cycle (Georgetown, Tex.) · 2016Article
- Hormesis: Decoding Two Sides of the Same Coin.Pharmaceuticals (Basel, Switzerland) · 2015Review
- Hormesis results in trade-offs with immunity.Evolution; international journal of organic evolution · 2014Article
- Nonlinear effects of nanoparticles: biological variability from hormetic doses, small particle sizes, and dynamic adaptive interactions.Dose-response : a publication of International Hormesis Society · 2014Article
- Integrative nanomedicine: treating cancer with nanoscale natural products.Global advances in health and medicine · 2014Review
- Different expression of miRNAs targeting helicases in rice in response to low and high dose rate γ-ray treatments.Plant signaling & behavior · 2013Article
- Testing the nanoparticle-allostatic cross-adaptation-sensitization model for homeopathic remedy effects.Homeopathy : the journal of the Faculty of Homeopathy · 2013Article
- A model for homeopathic remedy effects: low dose nanoparticles, allostatic cross-adaptation, and time-dependent sensitization in a complex adaptive system.BMC complementary and alternative medicine · 2012Article
- "Is hormesis applicable as a pro-healthy aging intervention in mammals and human beings, and how?" Introduction to a special issue of Dose-Response.Dose-response : a publication of International Hormesis Society · 2009Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
Hormesis is a common phenomenon in a number of biomedical areas. However, the basic nature of this phenomenon remains largely unknown. Therefore, significant uncertainty is inevitable in attempts to apply hormesis as a pro-health and anti-aging tool. Evidence supporting that hormetic-like effects may be the result of a generalized whole-organism adaptive epigenetic response is reviewed. Specific hormesis-inducing interventions during development would allow to achieve an optimal balance between activation and repression of various genes and thus to prevent age-related degenerative diseases and slow aging. The reasons that oscillating temperature mild stress could potentially be used for human application are discussed.
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Registered trials
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