Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2010
Improving antidepressant adherence and depression outcomes in primary care: the treatment initiation and participation (TIP) program.
Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Psychosocial interventions for late-life major depression: evidence-based treatments, predictors of treatment outcomes, and moderators of treatment effects.The Psychiatric clinics of North America · 2011Pooled it
- Predicting Medication Nonadherence in Older Adults With Difficult-to-Treat Depression in the IRL-GRey Randomized Controlled Trial.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022Trial
- Adherence to Depression Treatment in Primary Care: A Randomized Clinical Trial.JAMA psychiatry · 2017Trial
- Untangling therapeutic ingredients of a personalized intervention for patients with depression and severe COPD.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2014Trial
- Article
- A Review on Depression Care in the Philippines-Gaps and Recommendations for Better Patient Outcomes.Acta medica Philippina · 2024Review
- Psychosocial interventions to improve adherence in depressed and anxious older adults prescribed antidepressant pharmacotherapy: a scoping review.Therapeutic advances in psychopharmacology · 2023Article
- Antidepressant Adherence Among Hispanics: Patients in an Integrated Health Care Model.Journal of multidisciplinary healthcare · 2022Article
- Health care resource utilization and costs associated with nonadherence and nonpersistence to antidepressants in major depressive disorder.Journal of managed care & specialty pharmacy · 2021Article
- Transition Cliffs for Young Adults with Anxiety and Depression: Is Integrated Mental Health Care a Solution?The journal of behavioral health services & research · 2020Article
- The role of depression pharmacogenetic decision support tools in shared decision making.Journal of neural transmission (Vienna, Austria : 1996) · 2019Review
- Barriers and facilitators of adherence to antidepressants among outpatients with major depressive disorder: A qualitative study.PloS one · 2017Article
- Barriers to Mental Health Treatment in Rural Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015Article
- Predictors of outcomes for users of mental health rehabilitation services: a 5-year retrospective cohort study in inner London, UK.Social psychiatry and psychiatric epidemiology · 2013Article
- Medication beliefs and self-reported adherence among community-dwelling older adults.Clinical therapeutics · 2013Article
- Exploring robust methods for evaluating treatment and comparison groups in chronic care management programs.Population health management · 2013Article
- Late-Life Depression in Home Healthcare.Aging health · 2012Article
- Cognitive and behavioral predictors of light therapy use.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectiveTo test the impact of a novel psychosocial intervention to improve antidepressant adherence and depression outcomes among older adults prescribed pharmacotherapy by their primary care physician (PCP).
designA randomized controlled pilot study was conducted to examine the usefulness of the Treatment Initiation and Participation (TIP) program as an intervention to improve antidepressant adherence and depression outcomes.
settingThe study was conducted at two primary care clinics in New York city: one clinic served geriatric adults and the second clinic served a diverse group of mixed aged adults.
participantsThe sample consisted of adults aged 60 years and older with major depression who were recommended antidepressant therapy by their PCPs.
interventionAll participants were prescribed antidepressant therapy and randomly assigned to either the intervention (TIP) or the treatment as usual (TAU) group. The TIP intervention identifies and targets psychological barriers to depression care, especially stigma, as well as fears and misconceptions of depression and its treatment. TIP participants are encouraged to develop a treatment goal and create an adherence strategy. MEASUREMENT: Study participants were assessed at entry, 6, 12, and 24 weeks later. Adherence was measured based on self-report with chart verification. Depression severity was measured using the Hamilton Depression Rating Scale.
resultsParticipants in TIP were significantly more adherent to their antidepressant pharmacotherapy at all assessment time points and had a significantly greater decrease in depressive symptoms than older adults who received TAU.
conclusionThe results provide support for the usefulness of TIP as a brief intervention to improve adherence to depression medication treatment provided in primary care settings.
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