Evidence map›Paper›PMID 20220588›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2010

Collaborative depression treatment in older and younger adults with physical illness: pooled comparative analysis of three randomized clinical trials.

Kathleen Ell, María P Aranda, Bin Xie, Pey-Jiuan Lee, Chih-Ping Chou

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Antidepressants for the treatment of depression in people with cancer.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Pooled it
  3. Antidepressants for the treatment of depression in people with cancer.The Cochrane database of systematic reviews · 2015
    Pooled it
  4. Pooled it
  5. Depression interventions among racial and ethnic minority older adults: a systematic review across 20 years.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2012
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Treating post-CABG depression with telephone-delivered collaborative care: does patient age affect treatment and outcome?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2011
    Trial
  10. Trial
  11. Article
  12. Review
  13. Article
  14. Antidepressants for the treatment of depression in people with cancer.The Cochrane database of systematic reviews · 2023
    Review
  15. Article
  16. Perspectives on Training Needs for Geriatric Mental Health Providers: Preparing to Serve a Diverse Older Adult Population.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kathleen EllSchool of Social Work, University of Southern California, Los Angeles, CA 90089–0411, USA. ell@usc.edu
María P Aranda
Bin Xie
Pey-Jiuan Lee
Chih-Ping Chou
University of Southern California · USClaremont Graduate University · US

Funding

Multifaceted Depression Diabetes Program for HispanicsR01MH068468 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ELL, KATHLEEN R · 2005 to 2008
$3.1M
Multifaceted Oncology Depression Program for LatinosR01CA105269 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ELL, KATHLEEN R · 2004 to 2007
$2.7M
MULTIFACETED HOME CARE DEPRESSION PROGRAMR24MH061700 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ELL, KATHLEEN R · 2000 to 2003
$1.6M
NCI NIH HHS ADAPT-C R01CA105269NCI NIH HHS R01 CA105269NIMH NIH HHS HOPE-D R 24 MH61700NIMH NIH HHS MDDP R01 MH068468NIMH NIH HHS R01 MH068468NIMH NIH HHS R24 MH061700
6 · The paper itself

Abstract

objectiveThere have been few comparisons of the effectiveness of collaborative depression care between older versus younger adults with comorbid illness, particularly among low-income populations.

designIntent-to-treat analyses are conducted on pooled data from three randomized controlled trials that tested collaborative care aimed at improving depression, quality of life, and treatment receipt. SETTINGS: Trials were conducted in oncology and primary care safety net clinics and diverse home healthcare programs.

participantsThousand eighty-one patients with major depressive symptoms and cancer, diabetes, or other comorbid illness.

interventionSimilar intervention protocols included patient, provider, sociocultural, and organizational adaptations. MEASUREMENTS: The Patient Health Questionnaire (PHQ)-9 depression, Short-Form Health Survey-12/20 quality of life, self-reported hospitalization, ER, intensive care unit utilization, and antidepressant, psychotherapy treatment receipt are assessed at baseline, 6, and 12 months.

resultsThere are no significant differences in reducing depression symptoms (p ranged 0.18-0.58), improving quality of life (t = 1.86, df = 669, p = 0.07 for physical functioning at 12 months, and p ranged 0.23-0.99 for all others) patients aged between >/=60 years versus 18-59 years. Both age group intervention patients have significantly higher rates of a 50% PHQ-9 reduction (older: Wald chi[df = 1] = 4.82, p = 0.03; younger: Wald chi[df = 1] = 6.47, p = 0.02), greater reduction in major depression rates (older: Wald chi[df = 1] = 7.72, p = 0.01; younger: Wald chi[df = 1] = 4.0, p = 0.05) than enhanced-usual-care patients at 6 months and no significant age group differences in treatment type or intensity.

conclusionCollaborative depression care in individuals with comorbid illness is as effective in reducing depression in older patients as younger patients, including among low-income, minority patients. Patient, provider, and organizational adaptations of depression care management models may contribute to positive outcomes.

Indexed as

Age DistributionAge FactorsCombined Modality TherapyComorbidityDiabetes ComplicationsFemaleHome Care ServicesHumansMajor Depressive DisorderMaleNeeds AssessmentNeoplasmsPovertyQuality of LifeRandomized Controlled Trials as Topic

Identifiers

PMID20220588
PMCPMC2875343
OpenAlexW1973820612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.