ArticleJournal of virology2010
Visualizing viral dissemination in the mouse nervous system, using a green fluorescent protein-expressing Borna disease virus vector.
Article in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive-compulsive disorder.BMC psychiatry · 2022Article
- Construction of a Porcine Reproductive and Respiratory Syndrome Virus with Nanoluc Luciferase Reporter: a Stable and Highly Efficient Tool for Viral Quantification BothMicrobiology spectrum · 2022Article
- Avian Bornavirus Research-A Comprehensive Review.Viruses · 2022Review
- Genetic stability of the open reading frame 2 (ORF2) of borna disease virus 1 (BoDV-1) distributed in cattle in Hokkaido.The Journal of veterinary medical science · 2021Article
- Activation of ERK/CREB/BDNF pathway involved in abnormal behavior of neonatally Borna virus-infected rats.Neuropsychiatric disease and treatment · 2018Article
- West Nile Virus Infection in Human and Mouse Cornea Tissue.The American journal of tropical medicine and hygiene · 2016Article
- A novel intranuclear RNA vector system for long-term stem cell modification.Gene therapy · 2016Article
- piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals.RNA (New York, N.Y.) · 2015Article
- Development and application of reporter-expressing mononegaviruses: current challenges and perspectives.Antiviral research · 2014Review
- Production and purification of non replicative canine adenovirus type 2 derived vectors.Journal of visualized experiments : JoVE · 2013Article
- Analysis of borna disease virus trafficking in live infected cells by using a virus encoding a tetracysteine-tagged p protein.Journal of virology · 2013Article
- A novel porcine reproductive and respiratory syndrome virus vector system that stably expresses enhanced green fluorescent protein as a separate transcription unit.Veterinary research · 2013Article
- Recombinant canine distemper virus strain Snyder Hill expressing green or red fluorescent proteins causes meningoencephalitis in the ferret.Journal of virology · 2012Article
- A novel borna disease virus vector system that stably expresses foreign proteins from an intercistronic noncoding region.Journal of virology · 2011Article
- Intracerebral Borna disease virus infection of bank voles leading to peripheral spread and reverse transcription of viral RNA.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Borna disease virus (BDV) frequently persists in the brain of infected animals. To analyze viral dissemination in the mouse nervous system, we generated a mouse-adapted virus that expresses green fluorescent protein (GFP). This viral vector supported GFP expression for up to 150 days and possessed an extraordinary staining capacity, visualizing complete dendritic arbors as well as individual axonal fibers of infected neurons. GFP-positive cells were first detected in cortical areas from where the virus disseminated through the entire central nervous system (CNS). Late in infection, GFP expression was found in the sciatic nerve, demonstrating viral spread from the central to the peripheral nervous system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.