ArticleJournal of the Royal Society, Interface2010
Changing and shielded magnetic fields suppress c-Fos expression in the navigation circuit: input from the magnetosensory system contributes to the internal representation of space in a subterranean rodent.
Article in Journal of the Royal Society, Interface, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Review
- Hypomagnetic Field Induces the Production of Reactive Oxygen Species and Cognitive Deficits in Mice Hippocampus.International journal of molecular sciences · 2022Article
- Electrophysiology and the magnetic sense: a guide to best practice.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2022Review
- Corneal sensitivity is required for orientation in free-flying migratory bats.Communications biology · 2021Article
- Eyes are essential for magnetoreception in a mammal.Journal of the Royal Society, Interface · 2020Article
- Call-specific patterns of neural activation in auditory processing of Richardson's ground squirrel alarm calls.Brain and behavior · 2020Article
- Brain atlas of the African mole-rat Fukomys anselli.The Journal of comparative neurology · 2019Article
- Review
- Magnetocarcinogenesis: is there a mechanism for carcinogenic effects of weak magnetic fields?Proceedings. Biological sciences · 2018Review
- Zebrafish and medaka offer insights into the neurobehavioral correlates of vertebrate magnetoreception.Nature communications · 2018Article
- Biological effects of the hypomagnetic field: An analytical review of experiments and theories.PloS one · 2017Review
- Article
- Extracellular recordings reveal absence of magneto sensitive units in the avian optic tectum.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- Spontaneous expression of magnetic compass orientation in an epigeic rodent: the bank vole, Clethrionomys glareolus.Die Naturwissenschaften · 2014Article
- Odours stimulate neuronal activity in the dorsolateral area of the hippocampal formation during path integration.Proceedings. Biological sciences · 2014Article
- Magnetoreception in laboratory mice: sensitivity to extremely low-frequency fields exceeds 33 nT at 30 Hz.Journal of the Royal Society, Interface · 2013Article
- Rapid learning of magnetic compass direction by C57BL/6 mice in a 4-armed 'plus' water maze.PloS one · 2013Article
- Are stress responses to geomagnetic storms mediated by the cryptochrome compass system?Proceedings. Biological sciences · 2012Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neural substrate subserving magnetoreception and magnetic orientation in mammals is largely unknown. Previous experiments have demonstrated that the processing of magnetic sensory information takes place in the superior colliculus. Here, the effects of magnetic field conditions on neuronal activity in the rodent navigation circuit were assessed by quantifying c-Fos expression. Ansell's mole-rats (Fukomys anselli), a mammalian model to study the mechanisms of magnetic compass orientation, were subjected to natural, periodically changing, and shielded magnetic fields while exploring an unfamiliar circular arena. In the undisturbed local geomagnetic field, the exploration of the novel environment and/or nesting behaviour induced c-Fos expression throughout the head direction system and the entorhinal-hippocampal spatial representation system. This induction was significantly suppressed by exposure to periodically changing and/or shielded magnetic fields; discrete decreases in c-Fos were seen in the dorsal tegmental nucleus, the anterodorsal and the laterodorsal thalamic nuclei, the postsubiculum, the retrosplenial and entorhinal cortices, and the hippocampus. Moreover, in inactive animals, magnetic field intensity manipulation suppressed c-Fos expression in the CA1 and CA3 fields of the hippocampus and the dorsal subiculum, but induced expression in the polymorph layer of the dentate gyrus. These findings suggest that key constituents of the rodent navigation circuit contain populations of neurons responsive to magnetic stimuli. Thus, magnetic information may be integrated with multimodal sensory and motor information into a common spatial representation of allocentric space within this circuit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.