ArticleJournal of the American Society for Mass Spectrometry2010
Apparent inhibition by arginine of macrocyclic b ion formation from singly charged protonated peptides.
Article in Journal of the American Society for Mass Spectrometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- DNA Oligonucleotide Fragment Ion Rearrangements Upon Collision-Induced Dissociation.Journal of the American Society for Mass Spectrometry · 2015Article
- Peptide scrambling during collision-induced dissociation is influenced by N-terminal residue basicity.Journal of the American Society for Mass Spectrometry · 2014Article
- Gas-phase ion isomer analysis reveals the mechanism of peptide sequence scrambling.Analytical chemistry · 2014Article
- Evidence for sequence scrambling and divergent H/D exchange reactions of doubly-charged isobaric b-type fragment ions.Journal of the American Society for Mass Spectrometry · 2014Article
- Investigation of scrambled ions in tandem mass spectra. Part 1. Statistical characterization.Journal of the American Society for Mass Spectrometry · 2012Article
- Conformation-specific spectroscopy of peptide fragment ions in a low-temperature ion trap.Journal of the American Society for Mass Spectrometry · 2012Article
- Disfavoring macrocycle b fragments by constraining torsional freedom: the "twisted" case of QWFGLM b6.Journal of the American Society for Mass Spectrometry · 2012Article
- A pseudo MS3 approach for identification of disulfide-bonded proteins: uncommon product ions and database search.Journal of the American Society for Mass Spectrometry · 2012Article
- Occurrence of C-terminal residue exclusion in peptide fragmentation by ESI and MALDI tandem mass spectrometry.Journal of the American Society for Mass Spectrometry · 2012Article
- Mass spectrometry analysis of 2-nitrophenylhydrazine carboxy derivatized peptides.Journal of the American Society for Mass Spectrometry · 2011Article
- Sequencing Lys-N proteolytic peptides by ESI and MALDI tandem mass spectrometry.Journal of the American Society for Mass Spectrometry · 2011Article
- A systematic study of acidic peptides for b-type sequence scrambling.Journal of the American Society for Mass Spectrometry · 2011Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is now strong evidence for the existence of macrocyclic isomers of b(n)(+) ions, the formation and subsequent opening of which can lead to loss of sequence information from protonated peptides in multiple-stage tandem mass spectrometry experiments. In this study, the fragmentation patterns of protonated YARFLG and permuted isomers of the model peptide were investigated by collision-induced dissociation. Of interest was the potential influence of the arginine residue, and its position in the peptide sequence, on formation of the presumed macrocyclic b(5) ion isomer and potential loss of sequence information. We find that regardless of the sequence position (either internal or at the N- or C-terminus), only direct sequence ions or ions directly related to fragmentation of the arginine side chain are observed.
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