ArticleBMC infectious diseases2010
Description of two measles outbreaks in the Lazio Region, Italy (2006-2007). Importance of pockets of low vaccine coverage in sustaining the infection.
Article in BMC infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2021Pooled it
- Measles among healthcare workers in Italy: is it time to act?Human vaccines & immunotherapeutics · 2020Pooled it
- Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2020Pooled it
- Under-vaccinated groups in Europe and their beliefs, attitudes and reasons for non-vaccination; two systematic reviews.BMC public health · 2018Pooled it
- Antibiotics for preventing complications in children with measles.The Cochrane database of systematic reviews · 2013Pooled it
- Vaccines for measles, mumps and rubella in children.The Cochrane database of systematic reviews · 2012Pooled it
- Evolving measles status and immunization policy development in six European countries.Human vaccines & immunotherapeutics · 2022Review
- CVD Risk Factors in the Ukrainian Roma and Meta-Analysis of Their Prevalence in Roma Populations Worldwide.Journal of personalized medicine · 2021Article
- American and Canadian veterinarians' perceptions on dog and cat core vaccination rates and the impact of the human medicine anti-vaxx movement on veterinary medicine.The Canadian veterinary journal = La revue veterinaire canadienne · 2021Article
- Measles Outbreak in a Roma Community in the Eastern Region of Slovakia, May to October 2018.Zdravstveno varstvo · 2020Article
- Vaccine Hesitancy: A Growing Concern.Paediatric drugs · 2020Article
- Assessment of Economic Burden of Concurrent Measles and Rubella Outbreaks, Romania, 2011-2012.Emerging infectious diseases · 2019Article
- Austerity, measles and mandatory vaccination: cross-regional analysis of vaccination in Italy 2000-14.European journal of public health · 2019Article
- Impact of vaccination programs against measles, varicella and meningococcus C in Italy and in Tuscany and public health policies in the last decades.Journal of preventive medicine and hygiene · 2018Article
- Measles among migrants in the European Union and the European Economic Area.Scandinavian journal of public health · 2016Review
- Determinants of childhood vaccination completion at a peri-urban hospital in Kenya, December 2013 -January 2014: a case control study.The Pan African medical journal · 2015Article
- Hospital preparedness in community measles outbreaks-challenges and recommendations for low-resource settings.Emerging health threats journal · 2015Review
- Prevalence of measles antibodies among health care workers in Catalonia (Spain) in the elimination era.BMC infectious diseases · 2013Article
- Progress in the elimination of measles and congenital rubella in Central Italy.Human vaccines & immunotherapeutics · 2013Review
- Molecular epidemiology of measles virus in Italy, 2002-2007.Virology journal · 2012Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the launch of the national plan for measles elimination, in Italy, immunization coverage remains suboptimal and outbreaks continue to occur. Two measles outbreaks, occurred in Lazio region during 2006-2007, were investigated to identify sources of infection, transmission routes, and assess operational implications for elimination of the disease.
methodsData were obtained from several sources, the routine infectious diseases surveillance system, field epidemiological investigations, and molecular genotyping of virus by the national reference laboratory.
resultsOverall 449 cases were reported, sustained by two different stereotypes overlapping for few months. Serotype D4 was likely imported from Romania by a Roma/Sinti family and subsequently spread to the rest of the population. Serotype B3 was responsible for the second outbreak which started in a secondary school. Pockets of low vaccine coverage individuals (Roma/Sinti communities, high school students) facilitated the reintroduction of serotypes not endemic in Italy and facilitated the measles infection to spread.
conclusionsCommunities with low vaccine coverage represent a more serious public health threat than do sporadic susceptible individuals. The successful elimination of measles will require additional efforts to immunize low vaccine coverage population groups, including hard-to-reach individuals, adolescents, and young adults. An enhanced surveillance systems, which includes viral genotyping to document chains of transmission, is an essential tool for evaluating strategy to control and eliminate measles.
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