Evidence map›Paper›PMID 20217872›Full record

ArticleThe Journal of pathology2010

Anaplastic plasmacytomas: relationships to normal memory B cells and plasma cell neoplasms of immunodeficient and autoimmune mice.

Chen-Feng Qi, Dong-Mi Shin, Zhaoyang Li, Hongsheng Wang, Jianxum Feng, Janet W Hartley, Torgny N Fredrickson, Alexander L Kovalchuk, Herbert C Morse

Open access · greenAbstract read
In one paragraph

Article in The Journal of pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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  3. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chen-Feng QiLaboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
Dong-Mi Shin
Zhaoyang Li
Hongsheng Wang
Jianxum Feng
Janet W Hartley
Torgny N Fredrickson
Alexander L Kovalchuk
Herbert C Morse
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · US

Funding

Molecular Regulation of B-Cell Differentiation and FunctionZIAAI001024 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MORSE, HERBERT · 2009 to 2018
$8.3M
Lymphomas And Retroviral PathogenesisZIAAI000858 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MORSE, HERBERT · 2009 to 2018
$5.3M
Intramural NIH HHS ZIA AI000858
6 · The paper itself

Abstract

Anaplastic plasmacytomas (APCTs) from NFS.V(+) congenic mice and pristane-induced plasmacytic PCTs from BALB/c mice were previously shown to be histologically and molecularly distinct subsets of plasma cell neoplasms (PCNs). Here we extended these comparisons, contrasting primary APCTs and PCTs by gene expression profiling in relation to the expression profiles of normal naïve, germinal centre, and memory B cells and plasma cells. We also sequenced immunoglobulin genes from APCT and APCT-derived cell lines and defined surface phenotypes and chromosomal features of the cell lines by flow cytometry and by spectral karyotyping and fluorescence in situ hybridization. The results indicate that APCTs share many features with normal memory cells and the plasma cell-related neoplasms (PLs) of FASL-deficient mice, suggesting that APCTs and PLs are related and that both derive from memory B cells. Published in 2010 by John Wiley & Sons, Ltd.

Indexed as

Immunologic MemoryAnimalsBase SequenceB-Lymphocyte SubsetsCell SurvivalChromosome AberrationsGene Expression ProfilingImmunoglobulin Variable RegionMiceMice, Inbred BALB CMolecular Sequence DataMurine Acquired Immunodeficiency SyndromeNeoplasm ProteinsNeoplasms, Plasma CellOligonucleotide Array Sequence AnalysisPlasmacytomaImmunoglobulin Variable RegionNeoplasm Proteins

Identifiers

PMID20217872
PMCPMC3415987
OpenAlexW2137184198

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.