ArticleAdvanced materials (Deerfield Beach, Fla.)2010
Synthetic protocells to mimic and test cell function.
Article in Advanced materials (Deerfield Beach, Fla.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 72 citations in OpenAlex.
- Balanced activation of Nrf-2/ARE mediates the protective effect of sulforaphane on keratoconus in the cell mechanical microenvironment.Scientific reports · 2024Article
- Article
- Enhancing membrane-based soft materials with magnetic reconfiguration events.Scientific reports · 2022Article
- Chemically Triggered Coalescence and Reactivity of Droplet Fibers.Journal of the American Chemical Society · 2021Article
- Formation of Polarized, Functional Artificial Cells from Compartmentalized Droplet Networks and Nanomaterials, Using One-Step, Dual-Material 3D-Printed Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Reconfiguring droplet interface bilayer networks through sacrificial membranes.Biomicrofluidics · 2018Article
- Article
- Hierarchical Self-Assembly of a Copolymer-Stabilized Coacervate Protocell.Journal of the American Chemical Society · 2017Article
- Multiscale modeling of droplet interface bilayer membrane networks.Biomicrofluidics · 2015Article
- Contact bubble bilayers with flush drainage.Scientific reports · 2015Article
- A long-lasting concentration cell based on a magnetic electrolyte.Nature nanotechnology · 2014Article
- Developments in the tools and methodologies of synthetic biology.Frontiers in bioengineering and biotechnology · 2014Review
- Constructing droplet interface bilayers from the contact of aqueous droplets in oil.Nature protocols · 2013Article
- A tissue-like printed material.Science (New York, N.Y.) · 2013Article
- Droplet shape analysis and permeability studies in droplet lipid bilayers.Langmuir : the ACS journal of surfaces and colloids · 2012Article
- Engineering Polymersome Protocells.The journal of physical chemistry letters · 2011Article
- Safe and effective synthetic biology.Nature biotechnology · 2010Article
- Applications of biological pores in nanomedicine, sensing, and nanoelectronics.Current opinion in biotechnology · 2010Review
- Synthetic biology: an emerging research field in China.Biotechnology advancesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Synthetic protocells provide a new means to probe, mimic and deconstruct cell behavior; they are a powerful tool to quantify cell behavior and a useful platform to explore nanomedicine. Protocells are not simple particles; they mimic cell design and typically consist of a stabilized lipid bilayer with membrane proteins. With a finite number of well characterized components, protocells can be designed to maximize useful outputs. Energy conversion in cells is an intriguing output; many natural cells convert transmembrane ion gradients into electricity by membrane-protein regulated ion transport. Here, a synthetic cell system comprising two droplets separated by a lipid bilayer is described that functions as a biological battery. The factors that affect its electrogenic performance are explained and predicted by coupling equations of the electrodes, transport proteins and membrane behavior. We show that the output of such biological batteries can reach an energy density of 6.9 x 10(6) J m(-3), which is approximately 5% of the volumetric energy density of a lead-acid battery. The configuration with maximum power density has an energy conversion efficiency of 10%.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.