ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2010
The enhancement effect of beta-boswellic acid on hippocampal neurites outgrowth and branching (an in vitro study).
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The impact of GeNeurofil™ nutraceutical supplementation on psychometric assessment and biomarkers of neurodegeneration in cognitive impaired patients: a pilot study.European journal of clinical nutrition · 2026Trial
- Effect of 4 weeks of frankincense consumption on explicit motor memory and serum BDNF in elderly menTurkish journal of medical sciences · 2019Trial
- Role of Cytoskeletal Elements in Regulation of Synaptic Functions: Implications Toward Alzheimer's Disease and Phytochemicals-Based Interventions.Molecular neurobiology · 2024Review
- The journey of boswellic acids from synthesis to pharmacological activities.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity.Molecular neurobiology · 2022Article
- Inhibition Of Tau Protein Aggregation By a Chaperone-like β-Boswellic Acid Conjugated To Gold Nanoparticles.ACS omega · 2022Article
- Beta-Boswellic Acid Protects Against Cerebral Ischemia/Reperfusion Injury via the Protein Kinase C Epsilon/Nuclear Factor Erythroid 2-like 2/Heme Oxygenase-1 Pathway.Molecular neurobiology · 2022Article
- The Effect of Beta-Boswellic Acid on the Expression ofAdvanced pharmaceutical bulletin · 2020Article
- Kinetic and thermodynamic study of beta-Boswellic acid interaction with Tau protein investigated by surface plasmon resonance and molecular modeling methods.BioImpacts : BI · 2020Article
- Acetyl-11-keto-β-boswellic acid attenuates titanium particle-induced osteogenic inhibition via activation of the GSK-3β/β-catenin signaling pathway.Theranostics · 2019Article
- The Effects of Alpha Boswellic Acid on Reelin Expression and Tau Phosphorylation in Human Astrocytes.Neuromolecular medicine · 2017Article
- Effect of Boswellia papyrifera on cognitive impairment in multiple sclerosis.Iranian journal of neurology · 2014Article
- Caltubin, a novel molluscan tubulin-interacting protein, promotes axonal growth and attenuates axonal degeneration of rodent neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Evaluation of systemic administration of Boswellia papyrifera extracts on spatial memory retention in male rats.Journal of natural medicines · 2011Article
- The role of phytochemicals in the treatment and prevention of dementia.Drugs & aging · 2011Review
- Identifying frankincense impact by biochemical analysis and histological examination on rats.Saudi journal of biological sciences · 2011Article
- The effects of aqueous extract of Boswellia Serrata on hippocampal region CA1 and learning deficit in kindled rats.Research in pharmaceutical sciencesArticle
- Beneficial effect of Boswellia serrata gum resin on spatial learning and the dendritic tree of dentate gyrus granule cells in aged rats.Avicenna journal of phytomedicineArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Increasing evidences implicate impairment of axonal integrity in mechanisms underlying neurodegenerative disorders. Beta-boswellic acid (BBA) is the major component of Boswellia serrata gum. This resin has long been used in Ayurveda (India's traditional medicine) to prevent amnesia. In this study, the effect of BBA was examined on neurites outgrowth and branching as well as on polymerization dynamics of tubulin. The morphometric parameters (axonal length and neuritis branching) were examined microscopically after treating the hippocampal cells with BBA. Also the assembly process of tubulin was assessed using UV/V is spectrophotometer through following of absorbance at 350 nm. The results revealed that BBA could significantly enhance neurite outgrowth, branching, and tubulin polymerization dynamics. The obtained results suggest that enhancing effect of BBA on microtubule polymerization kinetics might be the origin of increasing axonal outgrowth and branching.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.