Trial reportEuropean journal of clinical nutrition2010
The study to investigate the potential benefits of probiotics in yogurt, a patient-oriented, double-blind, cluster-randomised, placebo-controlled, clinical trial.
Trial report in European journal of clinical nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00492583 (Study to Investigate the Potential of Probiotics in Yogurt), which is not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study to Investigate the Potential of Probiotics in Yogurt
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Safety of One of the Most Commonly Used Probiotic Strains: Systematic Review and Meta-analysis of Reported Adverse Events.Probiotics and antimicrobial proteins · 2026Pooled it
- The relationship between dairy products intake and breast cancer incidence: a meta-analysis of observational studies.BMC cancer · 2021Pooled it
- Probiotics for respiratory tract infections in children attending day care centers-a systematic review.European journal of pediatrics · 2018Pooled it
- Trial
- Supporting healthy weight in times of crisis: results of a one-year community health worker-led intervention among food (in)secure low-income Latinas.BMC public health · 2025Article
- Administration ofFrontiers in microbiology · 2023Article
- Guidance on the use of probiotics in clinical practice in children with selected clinical conditions and in specific vulnerable groups.Acta paediatrica (Oslo, Norway : 1992) · 2018Review
- Probiotics in Children: What Is the Evidence?Pediatric gastroenterology, hepatology & nutrition · 2017Review
- Article
- Usual Consumption of Specific Dairy Foods Is Associated with Breast Cancer in the Roswell Park Cancer Institute Data Bank and BioRepository.Current developments in nutrition · 2017Article
- The Association between Dairy Intake and Breast Cancer in Western and Asian Populations: A Systematic Review and Meta-Analysis.Journal of breast cancer · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProbiotic functional foods are widely advertised to consumers primarily based on probiotic supplements.
objectiveDetermine if consumption of yogurt containing a high dose of probiotics improves health in children ages 1-3 years attending daycare/school centers. SUBJECTS/
methodsDouble-blinded, randomized, placebo-controlled, allocation concealment clinical trial.
settingOutpatient participants in the Washington, DC area.
participants182 healthy children between the age of 1 and 3 years attending daycare/school at least 3 days a week.
interventionActive was a strawberry yogurt-based drink supplemented with Bifidobacterium animalis ssp. lactis (B. lactis) BB-12. The placebo was indistinguishable from the active drink, differing only in absence of the probiotic BB-12. Primary objective was to determine if consumption of a probiotic-containing yogurt-based drink decreases absences due to illnesses from daycare for children ages 1-3 years. Secondary was to determine if probiotic-containing yogurt-based drink improves overall parental satisfaction due to decreased absences from work and an overall healthier child.
resultsThere were no significant differences in the days of missed school per group, with 51.9% in the active group and 47.1% in the placebo group missing at least 1 day of school throughout the study. Additionally, there were no differences in any secondary outcomes among the groups.
conclusionsConsumption of a yogurt-based drink delivering 10(10) CFU of Bifidobacterium animalis ssp. lactis (B. lactis) BB-12 per day did not decrease the number of days missed of school due to an illness. Additional independent research on the potential of BB-12 to reduce illness in children needs to be conducted.
Indexed as
Identifiers
20216564What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.