ArticleAnesthesiology2010
Comparison of the utility of preoperative versus postoperative B-type natriuretic peptide for predicting hospital length of stay and mortality after primary coronary artery bypass grafting.
Article in Anesthesiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perioperative Biomarkers Predicting Postoperative Atrial Fibrillation Risk After Coronary Artery Bypass Grafting: A Narrative Review.Journal of cardiothoracic and vascular anesthesia · 2020Pooled it
- Effect of glutamate infusion on NT-proBNP after coronary artery bypass grafting in high-risk patients (GLUTAMICS II): A randomized controlled trial.PLoS medicine · 2022Trial
- The Value of Biomarkers in Major Cardiovascular Surgery Necessitating Cardiopulmonary Bypass.Reviews in cardiovascular medicine · 2024Review
- Free triiodothyronine (fT3) and B-type natriuretic peptide (BNP) predict in-hospital mortality after valve surgery.General thoracic and cardiovascular surgery · 2020Article
- Platelet-leukocyte aggregate is associated with adverse events after surgical intervention for rheumatic heart disease.Scientific reports · 2019Article
- Article
- A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury.American journal of respiratory and critical care medicine · 2017Article
- Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients.Anesthesiology · 2015Article
- Plasma corin decreases after coronary artery bypass graft surgery and is associated with postoperative heart failure: a pilot study.Journal of cardiothoracic and vascular anesthesia · 2015Observational
- Increased perioperative b-type natriuretic peptide associates with heart failure hospitalization or heart failure death after coronary artery bypass graft surgery.Anesthesiology · 2013Article
- High levels of B-type natriuretic peptide predict weaning failure from mechanical ventilation in adult patients after cardiac surgery.Clinics (Sao Paulo, Brazil) · 2013Article
- Assessment of preoperative B-type natriuretic peptide in adult surgeries: is it useful?Anesthesia and analgesia · 2011Article
- Increased peak postoperative B-type natriuretic peptide predicts decreased longer-term physical function after primary coronary artery bypass graft surgery.Anesthesiology · 2011Article
- Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.PloS one · 2011Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundPreoperative B-type natriuretic peptide (BNP) is known to predict adverse outcomes after cardiac surgery. The value of postoperative BNP for predicting adverse outcomes is less well delineated. The authors hypothesized that peak postoperative plasma BNP (measured postoperative days 1-5) predicts hospital length of stay (HLOS) and mortality in patients undergoing primary coronary artery bypass grafting, even after adjusting for preoperative BNP and perioperative clinical risk factors.
methodsThis study is a prospective longitudinal study of 1,183 patients undergoing primary coronary artery bypass grafting surgery. Mortality was defined as all-cause death within 5 yr after surgery. Cox proportional hazards analyses were conducted to separately evaluate the associations between peak postoperative BNP and HLOS and mortality. Multivariable adjustments were made for patient demographics, preoperative BNP concentration, and clinical risk factors. BNP measurements were log10 transformed before analysis.
resultsOne hundred fifteen deaths (9.7%) occurred in the cohort (mean follow-up = 4.3 yr, range = 2.38-5.0 yr). After multivariable adjustment for preoperative BNP and clinical covariates, peak postoperative BNP predicted HLOS (hazard ratio [HR] = 1.28, 95% CI = 1.002-1.64, P = 0.049) but not mortality (HR = 1.62, CI = 0.71-3.68, P = 0.25), whereas preoperative BNP independently predicted HLOS (HR = 1.09, CI = 1.01-1.18, P = 0.03) and approached being an independent predictor of mortality (HR = 1.36, CI = 0.96-1.94, P = 0.08). When preoperative and peak postoperative BNP were separately adjusted for within the clinical multivariable models, each independently predicted HLOS (preoperative BNP HR = 1.13, CI = 1.05-1.21, P = 0.0007; peak postoperative BNP HR = 1.44, CI = 1.15-1.81, P = 0.001) and mortality (preoperative BNP HR = 1.50, CI = 1.09-2.07, P = 0.01; peak postoperative BNP HR = 2.29, CI = 1.11-4.73, P = 0.02).
conclusionsPreoperative BNP may be better than peak postoperative BNP for predicting HLOS and longer term mortality after primary coronary artery bypass grafting surgery.
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