Evidence map›Paper›PMID 20216215›Full record

ReviewCurrent opinion in neurology2010

An update on the blood vessel in migraine.

K C Brennan, Andrew Charles

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 109 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. New-onset headache after transcatheter atrial septal defect closure: a systematic review.Indian journal of thoracic and cardiovascular surgery · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Migraine and Stroke: A Scoping Review.Journal of clinical medicine · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Evaluation of retinal vessel density and choriocapillaris flow in migraine patients with and without aura.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

K C BrennanDepartment of Neurology, David Geffen School of Medicine at UCLA, California, USA. kbrennan@mednet.ucla.edu
Andrew Charles
University of California, Los Angeles · US

Funding

Sex differences in the basic pathophysiology of migraineK08NS059072 · NINDS · UNIVERSITY OF UTAH · PI BRENNAN, KEVIN CHRISTOPHER · 2007 to 2011
$859k
Investigating the basic mechanisms linking migraine and strokeR21NS070084 · NINDS · UNIVERSITY OF UTAH · PI BRENNAN, KEVIN CHRISTOPHER · 2010 to 2011
$407k
NINDS NIH HHS K08 NS059072NINDS NIH HHS L30 NS063811NINDS NIH HHS R21 NS070084
6 · The paper itself

Abstract

purpose of reviewThe cranial blood vessel is considered an integral player in the pathophysiology of migraine, but its perceived role has been subject to much discussion and controversy over the years. We will discuss the evolution in our scientific understanding of cranial blood vessels (primarily arteries) in migraine. RECENT

findingsRecent developments have clarified the role of cranial blood vessels in the trigemino-vascular system and in cortical spreading depression. An underlying theme is the intimate relation between vascular activity and neural function, and we will emphasize the various roles of the blood vessel that go beyond delivering blood. We conclude that migraine cannot be understood, either from a research or clinical point of view, without an understanding of the vascular derangements that accompany it. SUMMARY: Migraine is accompanied by significant derangements in vascular function that may represent important targets for investigation and treatment.

Indexed as

AnimalsBrainCerebral ArteriesCerebrovascular CirculationHumansInflammation MediatorsMigraine DisordersModels, NeurologicalParasympathetic Fibers, PostganglionicSensory Receptor CellsTrigeminal NerveTrigeminal Nerve DiseasesInflammation Mediators

Identifiers

PMID20216215
PMCPMC5500293
OpenAlexW2084423618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.