Trial reportGenetics in medicine : official journal of the American College of Medical Genetics2010
Family history and perceptions about risk and prevention for chronic diseases in primary care: a report from the family healthware impact trial.
Trial report in Genetics in medicine : official journal of the American College of Medical Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Measurement of Perceived Risk of Developing Diabetes Mellitus: A Systematic Literature Review.Journal of general internal medicine · 2023Pooled it
- Impact of delivery models on understanding genomic risk for type 2 diabetes.Public health genomics · 2014Trial
- Using web-based familial risk information for diabetes prevention: a randomized controlled trial.BMC public health · 2013Trial
- Effect of preventive messages tailored to family history on health behaviors: the Family Healthware Impact Trial.Annals of family medicineTrial
- Health care providers' perceptions of screening for risk of type 1 diabetes in newborns using genetic risk scores.Journal of community genetics · 2026Article
- Outcomes of the national premarital genetic screening program for cystic fibrosis, homocystinuria, and spinal muscular atrophy in Qatar.Human genomics · 2026Article
- An Innovative Strategy for Collecting Family Health History: An Effectiveness-Implementation Trial in Primary Care Clinics.Annals of family medicine · 2025Article
- Transforming care with community breast pain clinics: a validated innovative solution benefitting patients and the healthcare system.BMJ open quality · 2025Article
- Family history of premature CHD and risk factor control in patients with a recent ACS.NPJ cardiovascular health · 2025Article
- The impact of perception bias for cardiovascular disease risk on physical activity and dietary habits.International journal of nursing sciences · 2024Article
- Article
- Health beliefs of unmarried adult Saudi individuals toward safe marriage and the role of premarital screening in avoiding consanguinity: a nationwide cross-sectional study.Frontiers in public health · 2024Article
- Dental cleaning behavior and related factors among hemodialysis patients in the West of Iran: A cross-sectional study.Clinical and experimental dental research · 2023Article
- Effect of lipid accumulation product on the development of hypertension among nondiabetic individuals in eastern China: A cross-sectional study.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Associations among risk perception, health efficacy, and health behaviors for cardiovascular disease: an application of risk perception attitude framework.Frontiers in cardiovascular medicine · 2023Article
- Interaction analysis of lipid accumulation product and family history of diabetes on impaired fasting glucose and diabetes risk in population with normotension in Eastern China: a community-based cross-sectional survey.Archives of public health = Archives belges de sante publique · 2022Article
- A qualitative study of perceptions of control over potential causes of death and the sources of information that inform perceptions of risk.Health psychology and behavioral medicine · 2022Article
- Perceived Nutrition and Health Concerns: Do They Protect against Unhealthy Dietary Patterns in Polish Adults?Nutrients · 2021Article
- Access to Personal Health Records and Screening for Breast and Cervical Cancer Among Women with a Family History of Cancer.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020Article
- Low Cardiovascular Disease Awareness in Chilean Women: Insights from the ESCI Project.Global heart · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 1 country.
Funding
Abstract
purposeTo determine whether family medical history as a risk factor for six common diseases is related to patients' perceptions of risk, worry, and control over getting these diseases.
methodsWe used data from the cluster-randomized, controlled Family Healthware Impact Trial (FHITr). At baseline, healthy primary care patients reported their perceptions about coronary heart disease, stroke, diabetes, and breast, ovarian, and colon cancers. Immediately afterward, intervention group participants used Family Healthware to record family medical history; this web-based tool stratified familial disease risks. Multivariate and multilevel regression analyses measured the association between familial risk and patient perceptions for each disease, controlling for personal health and demographics.
resultsFor the 2330 participants who used Family Healthware immediately after providing baseline data, perceived risk and worry for each disease were strongly associated with family history risk, adjusting for personal risk factors. The magnitude of the effect of family history on perceived risk ranged from 0.35 standard deviation for ovarian cancer to 1.12 standard deviations for colon cancer. Family history was not related to perceived control over developing diseases. Risk perceptions seemed optimistically biased, with 48-79% of participants with increased familial risk for diseases reporting that they were at average risk or below.
conclusionsParticipants' ratings of their risk for developing common diseases, before feedback on familial risk, parallels but is often lower than their calculated risk based on family history. Having a family history of a disease increases its salience and does not change one's perceived ability to prevent the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.