ArticleThe Plant cell2010
Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.
Article in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
75 citing papers in PubMed, 138 citations in OpenAlex.
- Research Progress on Regulatory Mechanisms of Conical Cell Morphogenesis inPlants (Basel, Switzerland) · 2026Review
- Stress-induced MAPK (SIMK)-dependent organization of microtubules in alfalfa.Molecular horticulture · 2026Article
- Signaling Pathway Analysis and Downstream Genes Associated with Disease Resistance Mediated byPlants (Basel, Switzerland) · 2026Article
- Sugar beet root susceptibility to storage rots and downregulation of plant defense genes increases with time in storage.Scientific reports · 2024Article
- Microtubule Regulation in Plants: From Morphological Development to Stress Adaptation.Biomolecules · 2023Review
- Article
- Location and Identification on Chromosome 3B of Bread Wheat of Genes Affecting Chiasma Number.Plants (Basel, Switzerland) · 2022Article
- Regulatory Mechanisms of Mitogen-Activated Protein Kinase Cascades in Plants: More than Sequential Phosphorylation.International journal of molecular sciences · 2022Review
- Mitogen-Activated Protein Kinase and Substrate Identification in Plant Growth and Development.International journal of molecular sciences · 2022Review
- MAP kinase cascades in plant development and immune signaling.EMBO reports · 2022Review
- Mitogen-Activated Protein Kinase 4-Regulated Metabolic Networks.International journal of molecular sciences · 2022Article
- Rice microtubule-associated protein OsMAP65-3.1, but not OsMAP65-3.2, plays a critical role in phragmoplast microtubule organization in cytokinesis.Frontiers in plant science · 2022Article
- The Protein Phosphatase PP2A Plays Multiple Roles in Plant Development by Regulation of Vesicle Traffic-Facts and Questions.International journal of molecular sciences · 2021Review
- Genome-Wide Identification and Analysis ofInternational journal of molecular sciences · 2021Article
- The Pepper Mitogen-Activated Protein Kinase CaMAPK7 Acts as a Positive Regulator in Response toFrontiers in microbiology · 2021Article
- TALEN-BasedFrontiers in plant science · 2021Article
- Receptor-Like Protein Kinases Function Upstream of MAPKs in Regulating Plant Development.International journal of molecular sciences · 2020Review
- Complementary Superresolution Visualization of Composite Plant Microtubule Organization and Dynamics.Frontiers in plant science · 2020Article
- Spatiotemporal Pattern of Ectopic Cell Divisions Contribute to Mis-Shaped Phenotype of Primary and Lateral Roots ofFrontiers in plant science · 2020Article
- Cortical Microtubule Organization during Petal Morphogenesis inInternational journal of molecular sciences · 2019Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A double homozygous recessive mutant in the Arabidopsis thaliana homologs of nucleus- and phragmoplast-localized kinase 2 (ANP2) and 3 (ANP3) genes and a homozygous recessive mutant in the mitogen-activated protein kinase 4 (MPK4) gene of Arabidopsis exhibit deficiencies in the overall microtubule (MT) organization, which result in abnormal cell growth patterns, such as branching of root hairs and swelling of diffusely growing epidermal cells. Genetic, pharmacological, molecular, cytological, and biochemical analyses show that the major underlying mechanism for these phenotypes is excessive MT stabilization manifested in both mutants as heavy MT bundling, disorientation, and drug stability. The above defects in MAPK signaling result in the adverse regulation of members of the microtubule-associated protein (MAP65) protein family, including strongly diminished phosphorylation of MAP65-1. These data suggest that ANP2/ANP3, MPK4, and the microtubule-associated protein MAP65-1, a putative target of MPK4 signaling, are all essential for the proper organization of cortical microtubules in Arabidopsis epidermal cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.