ArticleBMC infectious diseases2010
Population-based seroprevalence of HSV-2 and syphilis in Andhra Pradesh state of India.
Article in BMC infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Prevalence of herpes simplex virus 2 among MSM in Mainland China: a systematic review and meta-synthesis.AIDS research and therapy · 2022Pooled it
- A systematic review and meta-analysis of risk factors for sexual transmission of HIV in India.PloS one · 2012Pooled it
- Prevalence of CMV, EBV, HPV, and HSV among South Asian healthy population: A systematic review and meta-analysis.PLOS global public health · 2026Article
- A Contemporary Insight Into the Seroepidemiology of Herpes Simplex Virus Infection in the Sub-Himalayan Region: Seroepidemiology of HSV Infection in North India.TheScientificWorldJournal · 2025Article
- Combinatorial Effects of miRNAs in HSV-2 Infection of Macrophages: An In Silico and In Vitro Integration Approach.Vaccines · 2023Article
- Protocol: Mapping social networks, social influence and sexual health among youth in rural KwaZulu-Natal, the Sixhumene cohort study.Wellcome open research · 2022Article
- Seroprevalence and associated factors of HSV-2 infection among general population in Shandong Province, China.BMC infectious diseases · 2019Article
- Seroprevalence of Herpes Simplex Virus type-2 (HSV-2) among pregnant women who participated in a national HIV surveillance activity in Haiti.BMC infectious diseases · 2017Article
- Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in Arkhangelsk, Northwest Russia: a population-based cross-sectional study.BMC infectious diseases · 2016Article
- Population and dyadic-based seroincidence of herpes simplex virus-2 and syphilis in southern India.Sexually transmitted infections · 2015Article
- Seroprevalence of Herpes Simplex Virus Type 1 and 2 in Taiwan and Risk Factor Analysis, 2007.PloS one · 2015Article
- Serological Profile of HSV-2 in STD Patients: Evaluation of Diagnostic Utility of HSV-2 IgM and IgG Detection.Journal of clinical and diagnostic research : JCDR · 2014Article
- High prevalence of syphilis among street-based female sex workers in Nanchang, China.Indian dermatology online journal · 2014Article
- Sexually transmitted infections and male circumcision: a systematic review and meta-analysis.ISRN urology · 2013Article
- Social network and risk-taking behavior most associated with rapid HIV testing, circumcision, and preexposure prophylaxis acceptability among high-risk Indian men.AIDS patient care and STDs · 2012Article
- Field-based video pre-test counseling, oral testing, and telephonic post-test counseling: implementation of an HIV field testing package among high-risk Indian men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2012Article
- Behavioral and biomedical combination strategies for HIV prevention.Cold Spring Harbor perspectives in medicine · 2012Review
- Serum HSV-1 and 2 IgM in Sexually Transmitted Diseases - More for Screening Less for Diagnosis: An Evaluation of Clinical Manifestation.Journal of global infectious diseases · 2012Article
- A protective effect of circumcision among receptive male sex partners of Indian men who have sex with men.AIDS and behavior · 2012Article
- Wives without husbands: gendered vulnerability to sexually transmitted infections among previously married women in India.AIDS care · 2012Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundUnderstanding the prevalence and risk factors for common causes of ulcerative genital disease in the general population would inform current STI syndromic management and HIV testing strategies in high HIV prevalence regions of India.
methodsPersons 15-49 years old from 32 rural and 34 urban clusters were sampled using a stratified random method to represent adults in the high HIV prevalence Guntur district in Andhra Pradesh state. Interviews were conducted and dry blood spots were collected on 12,617 study participants. Testing for HSV-2 and syphilis was performed.
resultsAdjusted HSV-2 and syphilis seroprevalence rates were 4.70% and 2.08% for men and 7.07% and 1.42% for women. For men, tattooing, >3 lifetime sex partners, tobacco use, and sex with men in the past 6 months were associated with HSV-2 or syphilis (ORs, 1.66-2.95, p < 0.05). Male circumcision was positively associated with HSV-2 infection (OR, 1.37, p = 0.028) though this could be due to residual confounding. In women, greater than one lifetime partner remained significantly associated with HSV-2 in multivariate analysis (OR, 2.61; 95% CI, 1.39-4.87). Among all behavioral risk factors and other covariates in women and men, HIV infection exhibited the strongest association with HSV-2 and syphilis (ORs, 8.2-14.2, p < 0.001). The proportion of individuals with HSV-2 who were HIV infected was less than the proportion with syphilis who were HIV infected (11.8% vs. 22.7%; p = 0.001).
conclusionsNearly one in four persons surveyed in this population-based study that were seroprevalent for syphilis, were also HIV infected. Common population risk factors for syphilis, HSV-2 and HIV and high rates of co-seroprevalence suggest that HIV testing, STI testing and service strategies for these would benefit from direct linkage in India.
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