ReviewTissue engineering. Part A2010
Tissue-engineered three-dimensional tumor models to study tumor angiogenesis.
Review in Tissue engineering. Part A, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 49 citations in OpenAlex.
- Functional biomaterials for biomimetic 3D in vitro tumor microenvironment modeling.In vitro models · 2023Review
- Review
- Coaxially Bioprinted Cell-Laden Tubular-Like Structure for Studying Glioma Angiogenesis.Frontiers in bioengineering and biotechnology · 2021Article
- Bioprinting of 3D breast epithelial spheroids for human cancer models.Biofabrication · 2019Article
- Vascularized microfluidic platforms to mimic the tumor microenvironment.Biotechnology and bioengineering · 2018Article
- Assessing multiparametric drug response in tissue engineered tumor microenvironment models.Methods (San Diego, Calif.) · 2018Article
- Hydrogels to model 3D in vitro microenvironment of tumor vascularization.Advanced drug delivery reviews · 2014Review
- Personalized in vitro cancer modeling - fantasy or reality?Translational oncology · 2014Review
- The dominant role of IL-8 as an angiogenic driver in a three-dimensional physiological tumor construct for drug testing.Tissue engineering. Part A · 2014Article
- Hyaluronic acid hydrogel stiffness and oxygen tension affect cancer cell fate and endothelial sprouting.Biomaterials science · 2014Article
- Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche.Cancer research · 2013Article
- Modeling Ewing sarcoma tumors in vitro with 3D scaffolds.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Three-dimensional-engineered matrix to study cancer stem cells and tumorsphere formation: effect of matrix modulus.Tissue engineering. Part A · 2013Article
- Flow measurements in a blood-perfused collagen vessel using x-ray micro-particle image velocimetry.PloS one · 2013Article
- Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids.Biomaterials · 2012Article
- A microwell cell culture platform for the aggregation of pancreatic β-cells.Tissue engineering. Part C, Methods · 2012Article
- Hydroxyapatite nanoparticle-containing scaffolds for the study of breast cancer bone metastasis.Biomaterials · 2011Article
- Cancer Tissue Engineering: A Novel 3D Polystyrene Scaffold for In Vitro Isolation and Amplification of Lymphoma Cancer Cells from Heterogeneous Cell Mixtures.Journal of tissue engineering · 2011Article
- Tumor engineering: the other face of tissue engineering.Tissue engineering. Part A · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cell-microenvironment interactions play a critical role in the transformation of normal cells into cancer; however, the underlying mechanisms and effects are far from being well understood. Tissue Engineering provides innovative culture tools and strategies to study tumorigenesis under pathologically relevant culture conditions. Specifically, integration of biomaterials, scaffold fabrication, and micro/nano-fabrication techniques offers great promise to reveal the dynamic role of chemical, cell-cell, cell-extracellular matrix, and mechanical interactions in the pathogenesis of cancer. Due to the central importance of blood vessel formation in tumor growth, progression, and drug response, this review will discuss specific design parameters for the development of culture microenvironments to study tumor angiogenesis. Tumor engineering approaches have the potential to revolutionize our understanding of cancer, provide new platforms for testing of anti-cancer drugs, and may ultimately result in improved treatment strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.