ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life2010
Influence of montmorillonite on nucleotide oligomerization reactions: a molecular dynamics study.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Polymerization and replication of primordial RNA induced by clay-water interface dynamics.Communications chemistry · 2025Article
- Effect of montmorillonite K10 clay on RNA structure and function.Biophysical journal · 2024Article
- Potassium at the Origins of Life: Did Biology Emerge from Biotite in Micaceous Clay?Life (Basel, Switzerland) · 2022Article
- Clays and the Origin of Life: The Experiments.Life (Basel, Switzerland) · 2022Review
- How do Nucleotides Adsorb Onto Clays?Life (Basel, Switzerland) · 2018Article
- Systems protobiology: origin of life in lipid catalytic networks.Journal of the Royal Society, Interface · 2018Review
- Adsorption of nucleic Acid bases, ribose, and phosphate by some clay minerals.Life (Basel, Switzerland) · 2015Review
- Possible origin of life between mica sheets: does life imitate mica?Journal of biomolecular structure & dynamics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigate a proposed origins of life scenario involving the clay montmorillonite and its catalytic role in forming oligonucleotides from activated mononucleotides. Clay and mineral surfaces are important for concentrating the reactants and for promoting nucleotide polymerization reactions. Using classical molecular dynamics methods we provide atomic details of reactant conformations prior to polynucleotide formation, lending insight into previously reported experimental observations of this phenomenon. The simulations clarify the catalytic role of metal ions, demonstrate that reactions leading to correct linkages take place primarily in the interlayer, and explain the observed sequence selectivity in the elongation of the chain. The study comparing reaction probabilities involving L- and D-chiral forms of the reactants has found enhancement of homochiral over heterochiral products when catalyzed by montmorillonite.
Indexed as
Identifiers
20213159What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.