Evidence map›Paper›PMID 20212501›Full record

SynthesisSpinal cord2010

Neurogenic bowel management after spinal cord injury: a systematic review of the evidence.

A Krassioukov, J J Eng, G Claxton, B M Sakakibara, S Shum

2 registry-linked trialsOpen access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Spinal cord, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 91 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 7 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04914975 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect of Neuromuscular Electrical Stimulation on Bowel Management in People With Chronic Spinal Cord Injury - a Pilot Study

TypeinterventionalSponsorSwiss Paraplegic Research, NottwilRan2021 to 2024Enrolled20ConditionsElectric Stimulation Therapy, Bowel Dysfunction, Spinal Cord Injuries, Defecation DisorderArmsNeuromuscular electrical stimulation
NCT06587841 narecruitingnot on this mapstarted 2024, after this paper: background citation

Noninvasive Spinal Cord Neuromodulation to Improve Lower Urinary Tract Function After Spinal Cord Injury in Ukrainian War Veterans

TypeinterventionalSponsorUniversity of British ColumbiaRan2024 to 2027Enrolled60ConditionsSpinal Cord Injuries, Bowel Dysfunction, Sexual Dysfunction, Autonomic DysfunctionArmsSpinal COrd NEuromodulation™ (SCONE™) for transcutaneous spinal cord stimulation (TSCS)
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 7 syntheses or guidelines pooled it, 219 citations in OpenAlex.

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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

A KrassioukovInternational Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada. krassioukov@icord.org
J J Eng
G Claxton
B M Sakakibara
S Shum
GF Strong Rehabilitation Centre · CAInternational Collaboration On Repair Discoveries · CAUniversity of British Columbia · CAVancouver Coastal Health · CA

Funding

CIHR 63617CIHR MSH-63617
6 · The paper itself

Abstract

STUDY

designRandomized-controlled trials (RCTs), prospective cohort, case-control, pre-post studies, and case reports that assessed pharmacological and non-pharmacological intervention for the management of the neurogenic bowel after spinal cord injury (SCI) were included.

objectiveTo systematically review the evidence for the management of neurogenic bowel in individuals with SCI.

settingLiterature searches were conducted for relevant articles, as well as practice guidelines, using numerous electronic databases. Manual searches of retrieved articles from 1950 to July 2009 were also conducted to identify literature.

methodsTwo independent reviewers evaluated each study's quality, using Physiotherapy Evidence Database scale for RCTs and Downs and Black scale for all other studies. The results were tabulated and levels of evidence assigned.

resultsA total of 2956 studies were found as a result of the literature search. On review of the titles and abstracts, 57 studies met the inclusion criteria. Multifaceted programs are the first approach to neurogenic bowel and are supported by lower levels of evidence. Of the non-pharmacological (conservative and non-surgical) interventions, transanal irrigation is a promising treatment to reduce constipation and fecal incontinence. When conservative management is not effective, pharmacological interventions (for example prokinetic agents) are supported by strong evidence for the treatment of chronic constipation. When conservative and pharmacological treatments are not effective, surgical interventions may be considered and are supported by lower levels of evidence in reducing complications.

conclusionsOften, more than one procedure is necessary to develop an effective bowel routine. Evidence is low for non-pharmacological approaches and high for pharmacological interventions.

Indexed as

Databases, FactualGuidelines as TopicHumansNeurogenic BowelRandomized Controlled Trials as TopicSpinal Cord Injuries

Identifiers

PMID20212501
PMCPMC3118252
OpenAlexW2108057872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.