Evidence map›Paper›PMID 20212185›Full record

ArticleArchives of internal medicine2010

Potential use of 10-year and lifetime coronary risk information for preventive cardiology prescribing decisions: a primary care physician survey.

Stephen D Persell, Charles Zei, Kenzie A Cameron, Michael Zielinski, Donald M Lloyd-Jones

Abstract read
In one paragraph

Article in Archives of internal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Primary care physician use of patient race and polygenic risk scores in medical decision-making.Genetics in medicine : official journal of the American College of Medical Genetics · 2023
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  18. Short and lifetime cardiovascular risk estimates: same wine, different bottles. Do we have the COURAGE to abandon risk scores?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stephen D PersellNorthwestern University, Chicago, IL 60611, USA. spersell@nmff.org
Charles Zei
Kenzie A Cameron
Michael Zielinski
Donald M Lloyd-Jones
Northwestern University · US

Funding

Tailored Communication to Reduce Cardiovascular RiskK08HS015647 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERSELL, STEPHEN · 2006 to 2010
$628k
Epidemiologic Study of Ethnicity and Lifetime Risks for Cardiovascular DiseaseR21HL085375 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2006 to 2007
$297k
AHRQ HHS 1 K08 HS015647-01AHRQ HHS K08 HS015647NHLBI NIH HHS R21 HL085375
6 · The paper itself

Abstract

backgroundData are sparse regarding how physicians use coronary risk information for prescribing decisions.

methodsWe presented 5 primary prevention scenarios to primary care physicians affiliated with an academic center and surveyed their responses after they were provided with (1) patient risk factor information, (2) 10-year estimated coronary disease risk information, and (3) 10-year and lifetime risk estimates. We asked about aspirin prescribing, lipid testing, and lipid-lowering drug prescribing.

resultsOf 202 physicians surveyed, 99 (49%) responded. The physicians made guideline-concordant aspirin decisions 51% to 91% of the time using risk factor information alone. Providing 10-year risk estimates increased concordant aspirin prescribing when the 10-year coronary risk was moderately high (15%) and decreased guideline-discordant prescribing when the 10-year risk was low (2 of 4 cases). Providing the lifetime risk information sometimes increased guideline-discordant aspirin prescribing. The physicians selected guideline-concordant thresholds for initiating treatment with lipid-lowering drugs 44% to 75% of the time using risk factor information alone. Selecting too low or too high low-density lipoprotein cholesterol thresholds was common. Ten-year risk information improved concordance when the 10-year risk was moderately high. Providing lifetime risk information increased willingness to initiate pharmacotherapy at low-density lipoprotein cholesterol levels that were lower than those recommended by guidelines when the 10-year risk was low but the lifetime risk was high.

conclusionsProviding 10-year coronary risk information improved some hypothetical aspirin-prescribing decisions and improved lipid management when the short-term risk was moderately high. High lifetime risk sometimes led to more intensive prescription of aspirin or lipid-lowering medication. This outcome suggests that, to maximize the benefits of risk-calculating tools, specific guideline recommendations should be provided along with risk estimates.

Indexed as

Primary PreventionAdultAnticholesteremic AgentsAspirinCardiologyCoronary DiseaseDecision Support TechniquesDrug PrescriptionsFamily PracticeFemaleFibrinolytic AgentsGuideline AdherenceHealth Care SurveysHumansInternal MedicineLipidsAnticholesteremic AgentsAspirinFibrinolytic AgentsLipids

Identifiers

PMID20212185
PMCPMC3863113
OpenAlexW2093507291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.