ArticleProceedings of the National Academy of Sciences of the United States of America2010
Hose in Hose, an S locus-linked mutant of Primula vulgaris, is caused by an unstable mutation at the Globosa locus.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- A single dominant GLOBOSA allele accounts for repeated origins of hose-in-hose flowers in Sinningia (Gesneriaceae).The Plant cell · 2024Article
- Two floral forms in the same species-distyly.Planta · 2023Review
- Supergene evolution via stepwise duplications and neofunctionalization of a floral-organ identity gene.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Primula vulgaris (primrose) genome assembly, annotation and gene expression, with comparative genomics on the heterostyly supergene.Scientific reports · 2018Article
- Sequencing the genomic regions flanking S-linked PvGLO sequences confirms the presence of two GLO loci, one of which lies adjacent to the style-length determinant gene CYP734A50.Plant reproduction · 2017Article
- Oakleaf: an S locus-linked mutation of Primula vulgaris that affects leaf and flower development.The New phytologist · 2015Article
- Integration of genetic and physical maps of the Primula vulgaris S locus and localization by chromosome in situ hybridization.The New phytologist · 2015Article
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- Epigenetic imbalance and the floral developmental abnormality of the in vitro-regenerated oil palm Elaeis guineensis.Annals of botany · 2011Review
- Floral heteromorphy in Primula vulgaris: progress towards isolation and characterization of the S locus.Annals of botany · 2011Article
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Authors and funding
6 authors.
Funding
Abstract
Hose in Hose mutants of primrose and cowslip have been cultivated since the early 17th century and show dominant homeotic conversion of sepals to petals. The phenotype shows variable penetrance and expressivity and is linked to the S locus, which controls floral heteromorphy in Primula species. Here we demonstrate that the homeotic conversion of sepals to petals in Hose in Hose is associated with up-regulation of both Primula B-function MADS box genes PvDef and PvGlo in the first floral whorl. We have defined a restriction fragment length polymorphism associated with PvGlo that cosegregates with the Hose in Hose phenotype and have also identified and characterized a retrotransposon insertion in the PvGlo promoter which is associated with the up-regulated expression of PvGlo. Excision of this retrotransposon, associated with epigenetic changes at the locus, causes reversion toward normal calyces and restores wild-type flower development. These data define the molecular basis of the Hose in Hose mutation and provide an explanation for its long-documented phenotypic instability.
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