Evidence map›Paper›PMID 20211945›Full record

Trial reportPediatrics2010

An intervention to reduce environmental tobacco smoke exposure improves pregnancy outcomes.

Ayman A E El-Mohandes, Michele Kiely, Susan M Blake, Marie G Gantz, M Nabil El-Khorazaty

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 7 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 7 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. A Clustered Randomized Controlled Trial to Reduce Secondhand Smoke Exposure Among Nonsmoking Pregnant Women in Sichuan Province, China.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Risk of Gestational Diabetes Due to Maternal and Partner Smoking.International journal of environmental research and public health · 2022
    Observational
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ayman A E El-MohandesCollege of Public Health, University of Nebraska Medical Center, 984355 Nebraska Medical Center, Omaha, NE 68198-4355, USA. aelmohandes@unmc.edu
Michele Kiely
Susan M Blake
Marie G Gantz
M Nabil El-Khorazaty
RTI International · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USGeorge Washington University · USUniversity of Nebraska Medical Center · US

Funding

NIH DC INITIATIVE TO REDUCE INFANT MORTALITYU18HD031206 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI EL-KHORAZATY, NABIL · 1993 to 2003
$6.0M
NIH D.C. INITIATIVE TO REDUCE INFANT MORTALITYU18HD031919 · NICHD · HOWARD UNIVERSITY · PI JOHNSON, ALLAN ALEXANDER · 1993 to 2003
$3.8M
COOPERATIVE PERINATAL STUDIES AND INTERVENTIONSU18HD030445 · NICHD · GEORGETOWN UNIVERSITY · PI SIVASUBRAMANIAN, KOLINJAVADI N · 1992 to 2003
$3.7M
NIH D.C. INITIATIVE TO REDUCE INFANT MORTALITYU18HD036104 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI EL-MOHANDES, AYMAN A · 1998 to 2003
$2.7M
COOPERATIVE PERINATAL STUDIES AND INTERVENTIONSU18HD030447 · NICHD · CHILDREN'S NATIONAL MEDICAL CENTER · PI JOSEPH, JILL G. · 1992 to 2003
$1.7M
Intramural NIH HHS Z99 HD999999NICHD NIH HHS 3U18HD030445NICHD NIH HHS 3U18HD030447NICHD NIH HHS 3U18HD03919NICHD NIH HHS 5U18HD036104NICHD NIH HHS 5U18HD31206NICHD NIH HHS U18 HD030445NICHD NIH HHS U18 HD030447NICHD NIH HHS U18 HD031206NICHD NIH HHS U18 HD031919NICHD NIH HHS U18 HD036104
6 · The paper itself

Abstract

objectiveWe tested the efficacy of a cognitive-behavioral intervention in reducing environmental tobacco smoke exposure (ETSE) and improving pregnancy outcomes among black women.

methodsWe recruited 1044 women to a randomized, controlled trial during 2001-2004 in Washington, DC. Data on 691 women with self-reported ETSE were analyzed. A subset of 520 women with ETSE and salivary cotinine levels (SCLs) of <20 ng/mL were also analyzed. Individually tailored counseling sessions, adapted from evidence-based interventions for ETSE and other risks, were delivered to the intervention group. The usual-care group received routine prenatal care as determined by their provider. Logistic regression models were used to predict ETSE before delivery and adverse pregnancy outcomes.

resultsWomen in the intervention were less likely to self-report ETSE before delivery when controlling for other covariates (odds ratio [OR]: 0.50 [95% confidence interval (CI): 0.35-0.71]). Medicaid recipients were more likely to have ETSE (OR: 1.97 [95% CI: 1.31-2.96]). With advancing maternal age, the likelihood of ETSE was less (OR: 0.96 [95% CI: 0.93-0.99]). For women in the intervention, the rates of very low birth weight (VLBW) and very preterm birth (VPTB) were significantly improved (OR: 0.11 [95% CI: 0.01-0.86] and OR: 0.22 [95% CI: 0.07-0.68], respectively). For women with an SCL of <20 ng/mL, maternal age was not significant. Intimate partner violence at baseline significantly increased the chances of VLBW and VPTB (OR: 3.75 [95% CI: 1.02-13.81] and 2.71 [95% CI: 1.11-6.62], respectively). These results were true for mothers who reported ETSE overall and for those with an SCL of <20 ng/mL.

conclusionsThis is the first randomized clinical trial demonstrating efficacy of a cognitive-behavioral intervention targeting ETSE in pregnancy. We significantly reduced ETSE as well as VPTB and VLBW, leading causes of neonatal mortality and morbidity in minority populations. This intervention may reduce health disparities in reproductive outcomes.

Indexed as

Smoking PreventionAdolescentAdultCognitive Behavioral TherapyFemaleHumansInfant, NewbornPregnancyPregnancy OutcomePrenatal CareSmokingTobacco Smoke PollutionYoung AdultTobacco Smoke Pollution

Identifiers

PMID20211945
PMCPMC2923806
OpenAlexW1977981292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.