ArticleLipids in health and disease2010
Fatty acid extracts from Lucilia sericata larvae promote murine cutaneous wound healing by angiogenic activity.
Article in Lipids in health and disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Comparative effectiveness of debridement strategies for chronic lower-extremity wounds: a systematic review and network meta-analysis.Frontiers in medicine · 2026Pooled it
- Chitosan-fibrinogen-thrombin matrix accelerates re-epithelialization and cornification in a rat wound healing model.NPJ Regenerative medicine · 2026Article
- Protective effects of the bioactive peptide from maggots against skin flap ischemia‒reperfusion injury in rats.Heliyon · 2024Article
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- Metabolic reprogramming in skin wound healing.Burns & trauma · 2024Review
- Larval Therapy and Larval Excretions/Secretions: A Potential Treatment for Biofilm in Chronic Wounds? A Systematic Review.Microorganisms · 2023Review
- A human tissue-based assay identifies a novel carrion blowfly strain for maggot debridement therapy.Scientific reports · 2022Article
- Antimicrobial Activity of Lipid Extracts of Echinoderms in the Nhatrang Bay (South China Sea).Doklady. Biochemistry and biophysics · 2022Article
- The role ofVeterinary world · 2021Article
- Antibacterial fatty acids: An update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents.Progress in lipid research · 2021Review
- Bioactive Fatty Acids in the Resolution of Chronic Inflammation in Skin Wounds.Advances in wound care · 2020Review
- Polysaccharide extracted fromNutrition & metabolism · 2020Article
- Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis.American journal of translational research · 2020Article
- Pharmacological Properties of the Medical Maggot: A Novel Therapy Overview.Evidence-based complementary and alternative medicine : eCAM · 2018Review
- Fatty acid supplements improve hair coat condition in rhesus macaques.Journal of medical primatology · 2017Article
- Next Generation Sequencing Identifies Five Major Classes of Potentially Therapeutic Enzymes Secreted by Lucilia sericata Medical Maggots.BioMed research international · 2016Article
- Evaluation of larval density Cochliomyia macellaria F. (Diptera: Calliphoridae) for therapeutic use in the recovery of tegumentar injuries.Parasitology research · 2015Article
- Histological patterns in healing chronic wounds using Cochliomyia macellaria (Diptera: Calliphoridae) larvae and other therapeutic measures.Parasitology research · 2015Article
- Characterisation of the small RNAs in the biomedically important green-bottle blowfly Lucilia sericata.PloS one · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundfatty acids are considered to be effective components to promote wound healing and Lucilia sericata larvae are applied clinically to treat intractable wounds. We aimed to investigate the effect of fatty acid extracts from dried Lucilia sericata larvae on murine cutaneous wound healing as well as angiogenesis.
resultsOn day 7 and 10 after murine acute excision wounds creation, the percent wound contraction of fatty acid extracts group was higher than that of vaseline group. On day 3, 7 and 10 after wounds creation, the wound healing quality of fatty acid extracts group was better than that of vaseline group on terms of granulation formation and collagen organization. On day 3 after wounds creation, the micro vessel density and vascular endothelial growth factor expression of fatty acid extracts group were higher than that of vaseline group. Component analysis of the fatty acid extracts by gas chromatography-mass spectrometry showed there were 10 kinds of fatty acids in total and the ratio of saturated fatty acid, monounsaturated fatty acid and polyunsaturated fatty acid (PUFA) was: 20.57%:60.32%:19.11%.
conclusionsFatty acid extracts from dried Lucilia sericata larvae, four fifths of which are unsaturated fatty acids, can promote murine cutaneous wound healing probably resulting from the powerful angiogenic activity of the extracts.
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Registered trials
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