ArticleDiabetes technology & therapeutics2010
The effects of depression on metabolic control and quality of life in indigent patients with type 2 diabetes.
Article in Diabetes technology & therapeutics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Association between subthreshold depression and self-care behaviors in people with type 2 diabetes: a systematic review of observational studies.Systematic reviews · 2020Pooled it
- Depression and serum low-density lipoprotein: A systematic review and meta-analysis.Journal of affective disorders · 2016Pooled it
- Impact of social determinants of health on outcomes for type 2 diabetes: a systematic review.Endocrine · 2014Pooled it
- Effects of motivational enhancement therapy plus cognitive behaviour therapy on depressive symptoms and health-related quality of life in adults with type II diabetes mellitus: a randomised controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Trial
- Trial
- Global and regional level association between depression and glycemic control in type 2 diabetes mellitus: A systematic review and meta-analysis.Indian journal of psychiatry · 2026Review
- Poverty and Quality of Life Dimensions: A Cross-Sectional Study of Diabetic Patients in Morocco.Healthcare (Basel, Switzerland) · 2025Article
- Association between depression and diabetes among American adults using NHANES data from 2005 to 2020.Scientific reports · 2024Article
- Increased Levels of HbA1c in Individuals with Type 2 Diabetes and Depression: A Meta-Analysis of 34 Studies with 68,398 Participants.Biomedicines · 2022Review
- Influences of Demographic, Social Determinants, Clinical, Knowledge, and Self-Care Factors on Quality of Life in Adults With Type 2 Diabetes: Black-White Differences.Journal of racial and ethnic health disparities · 2022Article
- Mediating Role of Depressive Symptoms on the Association Between Neighborhood Social Cohesion and Quality of Life in Individuals with Type 2 Diabetes Mellitus.Patient preference and adherence · 2022Article
- Prevalence and factors associated with anxiety and depression among type 2 diabetes in Qassim: A descriptive cross-sectional study.Journal of Taibah University Medical Sciences · 2017Article
- Depression treatment and health-related quality of life among adults with diabetes and depression.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- Prevalence and Impact of Anxiety and Depression on Type 2 Diabetes in Tunisian Patients over Sixty Years Old.Depression research and treatment · 2013Article
- Depression in diabetes mellitus: a comprehensive review.Hippokratia · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe objective of this study was to assess differences in metabolic control and health-related quality of life (QOL) among depressed and nondepressed adults in an indigent population with type 2 diabetes. RESEARCH DESIGN AND
methodsSubjects completed validated surveys to assess depression and QOL. Depression was assessed with the Center for Epidemiological Studies-Depression Scale and defined as a score of > or =16. Metabolic control (hemoglobin A1C, total cholesterol, low-density lipoprotein [LDL] cholesterol, and high-density lipoprotein [HDL] cholesterol) measures were abstracted from medical records. We compared demographic characteristics, metabolic control, and QOL by depression status. Ordinary least squares regression was used to assess differences in QOL scores and metabolic control levels by depression status adjusting for covariates.
resultsIn the study sample (n = 201), approximately 20% (n = 40) were depressed. In unadjusted analyses, subjects with depression had significantly lower SF-12 physical component summary (PCS) scores (30.4 +/- 7.3 vs. 39.6 +/- 11.8, P < 0.001) and mental component summary (MCS) scores (32.8 +/- 10.5 vs. 48.9 +/- 9.2, P < or = 0.001) and significantly higher total cholesterol (209.3 +/- 72.1 vs. 186.6 +/- 50.9, P = 0.024) compared to those without depression. No significant differences were observed by depression status in hemoglobin A1C, LDL cholesterol, and HDL cholesterol. After adjustment for relevant covariates, depressed individuals continued to have lower SF-12 PCS (36.1 vs. 39.0, P < or = 0.001) and MCS (41.6 vs. 46.8, P < or = 0.001) scores, but the difference in total cholesterol levels was no longer significant.
conclusionsIn an indigent sample with type 2 diabetes, depression is significantly associated with decreased physical and mental components of QOL. This finding further reinforces the importance of addressing depression in all populations with type 2 diabetes.
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