ArticleJournal of biomedical optics
Real-time, closed-loop dual-wavelength optical polarimetry for glucose monitoring.
Article in Journal of biomedical optics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Photoacoustic Resonators for Non-Invasive Blood Glucose Detection Through Photoacoustic Spectroscopy: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- Non-Invasive Technologies in Wearable Glucose Monitoring: A Structured Overview for the Future.Biosensors · 2026Review
- Development of Non-Invasive Continuous Glucose Prediction Models Using Multi-Modal Wearable Sensors in Free-Living Conditions.Sensors (Basel, Switzerland) · 2025Article
- A low-power approach to optical glucose sensing via polarisation switching.Scientific reports · 2025Article
- Effects of Skin Blood Flow Fluctuations on Non-Invasive Glucose Measurement and a Feasible Blood Flow Control Method.Sensors (Basel, Switzerland) · 2025Article
- Non-invasive glucose prediction and classification using NIR technology with machine learning.Heliyon · 2024Article
- A Novel Biosensor for the Detection of Glucose Concentration Using the Dual-Peak Long Period Grating in the Near- to Mid-Infrared.Sensors (Basel, Switzerland) · 2024Article
- Noninvasive Glucose Sensing In Vivo.Sensors (Basel, Switzerland) · 2023Review
- Progress and Perspectives of Mid-Infrared Photoacoustic Spectroscopy for Non-Invasive Glucose Detection.Biosensors · 2023Review
- Noninvasive Blood Glucose Monitoring Systems Using Near-Infrared Technology-A Review.Sensors (Basel, Switzerland) · 2022Review
- A Contactless Glucose Solution Concentration Measurement System Based on Improved High Accurate FMCW Radar Algorithm.Sensors (Basel, Switzerland) · 2022Article
- Nanozyme-based colorimetric biosensor with a systemic quantification algorithm for noninvasive glucose monitoring.Theranostics · 2022Review
- Composite polarization systems for independent controlling polarization of two beams with different wavelengths.Biomedical optics express · 2021Article
- The Progress of Glucose Monitoring-A Review of Invasive to Minimally and Non-Invasive Techniques, Devices and Sensors.Sensors (Basel, Switzerland) · 2019Review
- Real-time compensation method for robust polarimetric determination of glucose in turbid media.Biomedical optics express · 2019Article
- Recent advances in application of biosensors in tissue engineering.BioMed research international · 2014Review
- Dual-wavelength polarimetric glucose sensing in the presence of birefringence and motion artifact using anterior chamber of the eye phantoms.Journal of biomedical optics · 2013Article
- Noninvasive glucose detection in human skin using wavelength modulated differential laser photothermal radiometry.Biomedical optics express · 2012Article
- In vivo glucose monitoring using dual-wavelength polarimetry to overcome corneal birefringence in the presence of motion.Diabetes technology & therapeutics · 2012Article
- Glucose sensing in human epidermis using mid-infrared photoacoustic detection.Biomedical optics express · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The development of a real-time, dual-wavelength optical polarimetric system to ultimately probe the aqueous humor glucose concentrations as a means of noninvasive diabetic glucose monitoring is the long-term goal of this research. The key impact of the work is the development of an approach for the reduction of the time-variant corneal birefringence due to motion artifact, which is still a limiting factor preventing the realization of such a device. Our dual-wavelength approach utilizes real-time, closed-loop feedback that employs a classical three-term feedback controller and efficiently reduces the effect of motion artifact that appears as a common noise source for both wavelengths. In vitro results are shown for the open-loop system, and although the dual-wavelength system helps to reduce the noise, it is shown that closed-loop control is necessary to bring the noise down to a sufficient level for physiological monitoring. Specifically, in vitro measurement results with the closed-loop dual-wavelength approach demonstrate a sensitivity of 12.8 mg/dl across the physiologic glucose range in the presence of time-variant test cell birefringence. Overall, it is shown that this polarimetric system has the potential to be used as a noninvasive measure of glucose for diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.