Evidence map›Paper›PMID 20206625›Full record

ReviewExperimental parasitology2010

Role of chemokines in regulation of immunity against leishmaniasis.

Steve Oghumu, Claudio M Lezama-Dávila, Angelica P Isaac-Márquez, Abhay R Satoskar

Abstract readReview
In one paragraph

Review in Experimental parasitology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. ExploitingCells · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Serum levels of CC chemokine ligands in cutaneous leishmaniasis patients.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  13. Modulation of Host Immune Response duringFrontiers in immunology · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. In-situ immune profile of polymorphic vs. macular Indian Post Kala-azar dermal leishmaniasis.International journal for parasitology. Drugs and drug resistance · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Steve OghumuDepartment of Pathology, The Ohio State University Medical Center, 1645 Neil Avenue, Columbus, OH 43210, USA.
Claudio M Lezama-Dávila
Angelica P Isaac-Márquez
Abhay R Satoskar
The Ohio State University Wexner Medical Center · USAutonomous University of Campeche · MXThe Ohio State University · US

Funding

Chemokines and regulation of T cell responses during infectionR56AI068829 · NIAID · OHIO STATE UNIVERSITY · PI SATOSKAR, ABHAY R · 2008 to 2009
$600k
Isolation of novel antileishmanial molecules from Pentalinon andrieuxii rootR21AI076309 · NIAID · OHIO STATE UNIVERSITY · PI SATOSKAR, ABHAY R · 2008 to 2009
$413k
Treatment of cutaneous leishmaniasis using Pentalinon andrieuxii root extractR21AT004160 · NCCIH · OHIO STATE UNIVERSITY · PI SATOSKAR, ABHAY R · 2009 to 2010
$411k
NCCIH NIH HHS AT004160NIAID NIH HHS AI068829NIAID NIH HHS AI076309NIAID NIH HHS R56 AI068829
6 · The paper itself

Abstract

Successful immunity to Leishmania depends on recruitment of appropriate immune effector cells to the site of infection and chemokines play a crucial role in the process. At the same time, Leishmania parasites possess the ability to modify the chemokine profiles of their host thereby facilitating establishment of progressive infection. Therapeutic and prophylactic strategies targeted at chemokines and their receptors provide a promising area for further research. This review highlights our current knowledge concerning the role of chemokines and their receptors in modulating leishmaniasis in both clinical settings and experimental disease models.

Indexed as

AnimalsChemokinesDisease Models, AnimalHumansLeishmaniaLeishmaniasis, CutaneousLeishmaniasis, VisceralReceptors, ChemokineChemokinesReceptors, Chemokine

Identifiers

PMID20206625
PMCPMC3661772
OpenAlexW2054943138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.